Conferences
23–28 March 2014, Whistler, British Columbia, Canada
Innate Immunity, Metabolism and Vascular Injury
A chronic low-grade inflammatory response is a defining feature of various metabolic diseases, including atherosclerosis, obesity, and type 2 diabetes. This smoldering inflammation in tissues, whether it is in the vascular bed, white adipose tissue or perivascular fat, is primarily mediated by the innate immune system.
Consequently, this Keystone Symposium on Innate Immunity, Metabolism and Vascular Injury will bring together leading investigators in areas of macrophage biology, vascular inflammation, atherosclerosis, and obesity-induced metabolic disease.
Sessions will encompass a broad range of topics highlighting the importance of and mechanisms by which innate immunity contributes to progression of metabolic diseases, including monocyte development and trafficking, macrophage activation in vascular bed and adipose tissues, and systems biology of myeloid cells. Exciting new developments in sensing of metabolic stress by inflammasomes, clearance of apoptotic cells by macrophages, and initiation of necrotic cell death programs will also be discussed.
These basic studies will be complemented by talks discussing new strategies for promoting plaque regression, and targeting innate inflammation to treat insulin resistance, type 2 diabetes, and coronary artery disease.
http://www.keystonesymposia.org/index.cfm?e=web.Meeting.Program&meetingid=1260
