Sickle Cell Disease
A special issue of Medical Sciences (ISSN 2076-3271).
Deadline for manuscript submissions: 31 December 2026 | Viewed by 1355
Editor
Special Issue Information
Dear Colleagues,
Sickle cell disease (SCD) is known as the first "molecular disease" based on Linus Pauling's 1949 demonstration of an abnormal hemoglobin protein. Currently, FDA-approved pharmacological treatments and gene editing therapies are utilized to improve the health and quality of life of patients. This Special Issue will include manuscripts on all translational stages of SCD research, covering, but not limited to, the following topics: the basic science that led to an understanding of how the defective beta globin molecule results in sickling, pain and organ damage; the use of omics to identify biomarkers of sickle cell severity; SCD animal models that provide a better understanding of the pathophysiology while allowing the preclinical testing of therapeutics; and the pharmacologic and gene therapy clinical trials that have provided newly approved treatments leading to improved health outcomes and cures for the first molecular disease.
Prof. Dr. Steven R. Goodman
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Medical Sciences is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- sickle cell disease
- hemoglobin
- vaso-occlusion
- anemia
- genomics
- epigenomics
- proteomics
- metabolomics
- gene therapy
- clinical trials
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