Exposure and Risk in the Laboratory

A special issue of Laboratories (ISSN 2813-8856).

Deadline for manuscript submissions: 31 May 2025 | Viewed by 788

Special Issue Editor


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Guest Editor
School of Occupational and Public Health, Toronto Metropolitan University, Toronto, ON M5B 2K3, Canada
Interests: exposure assessment; evaluation of interventions; risk assessment; hazardous drugs; food processing; quantitative analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A laboratory is a setting known for research and development, student learning opportunities, and discovering new knowledge.  However, what many do not realize is that a laboratory is associated with numerous hazards, including chemicals such as solvents and acids, biological agents such as bacteria and other infectious agents, physical agents such as radiation and noise, safety hazards such as moving parts and slips, as well as ergonomic hazards such as awkward postures and poor lighting.  One or more of these hazards can be found within a single laboratory.  All these hazards represent short-term and long-term risks to lab users and visitors.  There have been numerous reports of fatalities occurring in both academic and industrial laboratories (https://www.labsafety.org/memorial-wall).  Despite our awareness of the importance of health and safety, these fatal incidents are still occurring to this day.  It is therefore important to obtain evidence-based data regarding the magnitude of the exposures and associated risks to protect the hundreds of thousands of workers and students who work in laboratory settings.  This Special Issue aims to publish cutting-edge research that examines exposure and risk in the laboratory to prevent incidents from occurring in these settings.

Dr. Chun-Yip Hon
Guest Editor

Manuscript Submission Information

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Keywords

  • academic laboratory
  • industrial laboratory
  • exposure assessment
  • risk analyses
  • mitigation of risk

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Published Papers (1 paper)

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Review

13 pages, 511 KiB  
Review
Comprehensive Assessment of Carbon Disulfide Exposure in Laboratories—Air and Biological Monitoring Approaches
by Jimmy Hu
Laboratories 2024, 1(3), 135-147; https://doi.org/10.3390/laboratories1030011 - 6 Nov 2024
Viewed by 533
Abstract
Carbon disulfide (CS2) is a highly toxic and flammable solvent extensively used in chemical processes and laboratory analyses. This review examines both air and biological monitoring methods for assessing the exposure of laboratory workers to CS2. Emphasis is placed [...] Read more.
Carbon disulfide (CS2) is a highly toxic and flammable solvent extensively used in chemical processes and laboratory analyses. This review examines both air and biological monitoring methods for assessing the exposure of laboratory workers to CS2. Emphasis is placed on the measurement of airborne CS2 concentrations and the monitoring of 2-thiothiazolidine-4-carboxylic acid (TTCA) in urine, a key biomarker of exposure. By analysing case studies and practical applications, the paper outlines the effectiveness and limitations of current monitoring techniques. Additionally, the review addresses key challenges such as CS2 volatility, dietary influence on biomarker levels, and the sufficiency of protective measures, including nitrile gloves. It also proposes best practices to mitigate exposure, such as improved ventilation, the use of polyvinyl alcohol gloves, and the substitution of CS2 with less hazardous solvents. This comprehensive review underscores the need for continuous vigilance in managing chemical exposure and offers insights into how laboratories can better protect their workers by integrating air and biological monitoring strategies. Full article
(This article belongs to the Special Issue Exposure and Risk in the Laboratory)
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