Antifungal Stewardship in Immunocompromised Hosts

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Pathogenesis and Disease Control".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 67

Special Issue Editors


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Guest Editor
1. Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain
2. Instituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain
Interests: invasive fungal infections; solid organ transplant; endocarditis; aspergillosis; antifungal stewardship
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Guest Editor
1. Department of Health Sciences, University of Genoa, 16126 Genoa, Italy
2. Clinica Malattie Infettive, Ospedale Policlinico San Martino–IRCCS, 16132 Genoa, Italy
Interests: candidemia; invasive aspergillosis; rare mould infections; invasive candidiasis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Antifungal stewardship programs (AFSPs) are increasingly recognized as crucial components of antimicrobial stewardship in hospitals and healthcare systems. Their relevance is based on the rising burden of fungal infections, the emergence of new antifungal drugs and the challenges in diagnosing invasive fungal infections (IFIs).

In recent years, we have experienced an increase in IFIs, especially in immunocompromised patients (e.g., transplant recipients, hematologic malignancies, ICU patients), with a high morbidity and mortality. At the same time, the incidence of resistant pathogens (e.g., Candida auris, azole-resistant Aspergillus fumigatus) is increasing globally.

On the other hand, the antifungal armamentarium is also increasing, and a small number of antifungal drugs have had to be used compared to antibacterials; however, in recent years, new antifungal families and new action mechanisms are emerging. These new drugs are costly and must be used wisely.

The diagnosis of IFIs is sometime difficult to confirm, leading to both under-treatment (delays in starting therapy) and over-treatment (empirical or prophylactic use in patients without proven infection).

In this Special Issue, we are interested in reviewing the different approaches of antifungal stewardship programs, the main common problems in their implementation, and new insights into the topic.

Dr. Maricela Valerio Minero
Dr. Antonio Vena
Guest Editors

Manuscript Submission Information

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Keywords

  • antifungal stewardship
  • invasive fungal infections
  • fungal disease

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Published Papers

This special issue is now open for submission.
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