Genomics of Fungal Plant Pathogens, 4th Edition

A special issue of Journal of Fungi (ISSN 2309-608X).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 97

Special Issue Editors


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Guest Editor
1. Fujian Key Laboratory on Conservation and Sustainable Utilization of Marine Biodiversity, Fuzhou Institute of Oceanography, Minjiang University, Fuzhou 350108, China
2. Fujian Universities Key Laboratory for Plant Microbe Interaction, Fujian Agriculture and Forestry University, Fuzhou 350002, China
Interests: plant-fungal interactions
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Guest Editor
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangdong Province Key Laboratory of Microbial Signals and Disease Control, Integrative Microbiology Research Centre, South China Agricultural University, Guangzhou 510642, China
Interests: phytopathogenic fungi; genes; virulence; transcription factors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Fungi cause most of the severe plant diseases that endanger food safety worldwide. Resistance to fungal pathogens is a major target of breeders; however, the unexpected mutation of avirulence genes has caused a boom and burst cycle in resistance and resistance breakdown. Fungicide-based chemical control is still the most important method to control plant fungal diseases, but most fungicides induce fungi to develop fungicide resistance. Many scientists are working on these aspects to develop ecological control strategies for plant fungal diseases. Recent advances in sequencing technologies have led to remarkable progress in understanding plant–fungal interactions based on the dissection of fungal genomes. Many important plant pathogenic fungi have successfully been studied using the second and third-generation sequencing approaches. Increasingly, functional genomics, proteomics, and metabolomics are being applied to study plant fungal pathogens. The development of advanced genomic tools and infrastructure is also making great progress. These increasing amounts of data will provide useful information to improve our understanding of the molecular mechanisms involved in host–pathogen interactions, in order to better understand fungal genome features, such as repetitive sequences, telomeres, conserved syntenic blocks, and the expansion of pathogenicity-related genes. The findings of these studies can be exploited to optimize beneficial interactions and to develop new plant-protection strategies.

This Special Issue is aimed at compiling research, reviews, and opinion articles covering new scientific discoveries in plant–fungal genomics. Articles covering new insights in genomic sequencing, functional genomics, proteomics, metabolomics, molecular biology, ecology dissection, and the molecular mechanisms involved in plant–fungal interactions at the genome level are welcomed.

Prof. Dr. Zonghua Wang
Prof. Dr. Yizhen Deng
Guest Editors

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Keywords

  • plant pathogen
  • genomic sequencing
  • functional genomics
  • molecular biology

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Published Papers (1 paper)

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Research

16 pages, 2971 KiB  
Article
Type 2C Protein Phosphatase MoPtc6 Plays Critical Roles in the Development and Virulence of Magnaporthe oryzae
by Frankline Otieno Jagero, Abah Felix, Yakubu Saddeeq Abubakar, Meilian Chen, Wilfred M. Anjago, Hatungimana Mediatrice, Nkurikiyimfura Oswald, Osakina Aron, Wei Tang, Zonghua Wang and Jules Biregeya
J. Fungi 2025, 11(5), 335; https://doi.org/10.3390/jof11050335 - 24 Apr 2025
Viewed by 152
Abstract
Rice blast caused by Magnaporthe oryzae pathotype is the worst disease that leads to serious food insecurity globally. Understanding rice blast disease pathogenesis is therefore essential for the development of a blast disease mitigation strategy. Reverse phosphorylation mediated by phosphatases performs a vital [...] Read more.
Rice blast caused by Magnaporthe oryzae pathotype is the worst disease that leads to serious food insecurity globally. Understanding rice blast disease pathogenesis is therefore essential for the development of a blast disease mitigation strategy. Reverse phosphorylation mediated by phosphatases performs a vital function in the activation of diverse biological mechanisms within eukaryotic. However, little has been reported on the roles of PP2Cs in the virulence of blast fungus. In this current work, we deployed functional genomics and biochemical approaches to characterize type 2C protein phosphatase MoPtc6 in blast fungus. Deletion of MoPTC6 led to a drastic reduction in conidiophore development, conidia production, hyphal growth, and stress tolerance. Western blotting assay demonstrated that the phosphorylation level of MoOsm1 was decreased while MoMps1 was increased in the MoPtc6 deletion mutant, and comparative transcriptome assay revealed a higher number of expressed genes between mutant and wild type. Localization assay confirmed that MoPtc6 is sub-localized in the cytoplasm of mycelia, spores, and in the appressoria of M. oryzae. Furthermore, disruption of MoPTC6 impaired appressoria turgor pressure and glycogen utilization; more findings revealed attenuation of hyphal penetration and virulence upon deletion of MoPTC6. Generally, present findings suggested the role of MoPtc6 in the growth and virulence of M. oryzae. Full article
(This article belongs to the Special Issue Genomics of Fungal Plant Pathogens, 4th Edition)
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