Special Issue "Leveraging Yeast Genetics to Model Evolutionarily Conserved Aspects of Human Disease"

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Genomics, Genetics and Molecular Biology".

Deadline for manuscript submissions: 30 November 2023 | Viewed by 69

Special Issue Editor

Dr. John L Hartman IV
E-Mail Website
Guest Editor
Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Interests: yeast genetics; cystic fibrosis; aging; cellular quiescence; cancer; phenomic models of disease

Special Issue Information

Dear Colleagues,

Yeast genetics has led the way for biological exploration to ultimately understand many aspects of human disease. Examples include fundamental roles of the central dogma, the cell cycle, protein trafficking, mitochondrial function, epigenetics, and other processes underlying disease. The power of yeast as a genetic model derives primarily from its relatively simple, unicellular eukaryotic nature and several unique organismal characteristics, rendering it especially amenable to genetic analysis. Despite remarkable contributions to understanding the biology of human diseases, yeast continues to harbor potential that is relatively untapped for this purpose. For example, the evidence for genetic complexity underlying human biology and disease continues to increase, as does the utility of yeast genetics to address it. This Special Issue has a purposefully broad scope to help to accomplish the objective of illuminating the complex genetics of cellular processes contributing to human disease and how analyses in yeast can be leveraged to address it through integrative biology. We invite all colleagues with passion for this topic to summarize, demonstrate, and/or propose how yeast genetic analysis, including phenomic modeling, complements studies in human or other models to inform our understanding of disease and thus discover and advance genetic-based therapeutic strategies.

Dr. John L Hartman IV
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • yeast genetics
  • human disease
  • S. cerevisiae
  • S. pombe
  • phenomic modeling
  • integrative biology

Published Papers

This special issue is now open for submission.
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