Special Issue "Nutrition, Genetics, and Cardiovascular Disease"

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425).

Deadline for manuscript submissions: 15 September 2019.

Special Issue Editors

Guest Editor
Prof. Marwan El Ghoch

1: Department of Nutrition and Dietetics, Faculty of Health Sciences—Beirut Arab University, Beirut, Lebanon
2: CTR Centre of Rehabilitation Therapy, Reggio Emilia, Italy
Website 1 | Website 2 | E-Mail
Interests: obesity treatment; genetics; sarcopenic obesity; genomics; weight-related cardio-metabolic diseases
Guest Editor
Dr. Said El Shamieh

Department of Medical Laboratory Technology, Faculty of Health Sciences—Beirut Arab University, Beirut, Lebanon
Website | E-Mail
Interests: obesity treatment; genetics; sarcopenic obesity; genomics; weight-related cardio-metabolic diseases

Special Issue Information

Dear Colleagues,

The Journal of Cardiovascular Development and Disease (JCDD) is launching a Special Issue on “Nutrition, Genetics, and Cardiovascular Disease”. JCDD is a peer-reviewed online journal, in its fourth year of existence, which publishes review articles and original works on cardiovascular development and disease.

It is well documented that cardiovascular disease is a major cause of death worldwide, in which genetic and environmental factors seem to play a determinant role. In fact, several dietary factors and nutritional-related diseases (i.e., obesity, type 2 diabetes) are strongly associated with cardiovascular diseases. In addition, genome-wide association studies have also identified numerous genomic loci that determine susceptibility to cardiovascular events. Therefore, nutrition and genetics seem to interact in predisposing an individual to cardiovascular diseases.

This Special Issue will provide a platform for the presentation of recent advances in knowledge on nutrition, genetics, and cardiovascular disease coming from diverse scientific disciplines.

Prof. Marwan El Ghoch
Dr. Said El Shamieh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • genetics
  • cardiovascular diseases
  • obesity
  • GWAS
  • sarcopenic obesity
  • type 2 diabetes
  • epigenetics
  • metabolic syndrome

Published Papers (3 papers)

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Research

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Open AccessArticle
Dietary Adherence of Saudi Males to the Saudi Dietary Guidelines and Its Relation to Cardiovascular Diseases: A Preliminary Cross-Sectional Study
J. Cardiovasc. Dev. Dis. 2019, 6(2), 17; https://doi.org/10.3390/jcdd6020017
Received: 2 February 2019 / Revised: 30 March 2019 / Accepted: 2 April 2019 / Published: 4 April 2019
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Abstract
Cardiovascular disease (CVD) is a major public health problem in Saudi Arabia. Dietary intake plays a major role in CVD incidence; however, the dietary intake status in Saudi nationals with CVD is unknown. We aimed to investigate whether the dietary patterns of Saudi [...] Read more.
Cardiovascular disease (CVD) is a major public health problem in Saudi Arabia. Dietary intake plays a major role in CVD incidence; however, the dietary intake status in Saudi nationals with CVD is unknown. We aimed to investigate whether the dietary patterns of Saudi males, using the Saudi dietary guidelines adherence score, in parallel with the measurement of a selective number of cardiovascular disease-related biomarkers, are contributing factors to CVD risk. Demographics, dietary adherence score, and blood biomarker levels were collected for 40 CVD patients and forty non-CVD patients. Fasting blood glucose (p = 0.006) and high-density lipoprotein levels (p = 0.03) were significantly higher in CVD patients. The adherence score to the Saudi dietary guidelines was not significantly different between the CVD and non-CVD patients; however, the specific adherence scores of fruit (p = 0.02), olive oil (p = 0.01), and non-alcoholic beer (p = 0.02) were significantly higher in the non-CVD patients. The differences in CVD family history (p = 0.02) and adherence scores to specific groups/foods between the CVD and non-CVD patients may contribute to CVD risk in Saudi males. However, as the sample size of this study was small, further research is required to validate these findings. Full article
(This article belongs to the Special Issue Nutrition, Genetics, and Cardiovascular Disease)

Review

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Open AccessReview
Association Between Smoking Hookahs (Shishas) and Higher Risk of Obesity: A Systematic Review of Population-Based Studies
J. Cardiovasc. Dev. Dis. 2019, 6(2), 23; https://doi.org/10.3390/jcdd6020023
Received: 28 May 2019 / Revised: 10 June 2019 / Accepted: 14 June 2019 / Published: 16 June 2019
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Abstract
The American Heart Association has published a scientific statement on the effect of hookah smoking on health outcomes; nevertheless, hookah smoking continues to be popular worldwide, especially among the young. Recent reports mention a potential link between hookah smoking and obesity; however, uncertainties [...] Read more.
The American Heart Association has published a scientific statement on the effect of hookah smoking on health outcomes; nevertheless, hookah smoking continues to be popular worldwide, especially among the young. Recent reports mention a potential link between hookah smoking and obesity; however, uncertainties still surround this issue. The aim of the current study was to conduct a systematic review to clarify whether hookah smoking is associated with a higher risk of obesity among the general population. This study was conducted in compliance with the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, and data were collated by means of a meta-analysis and a narrative synthesis. Of the 818 articles retrieved, five large-population and low-bias studies comprising a total of 16,779 participants met the inclusion criteria and were reviewed. All included studies reported that, regardless of gender, hookah smoking increases the risk of obesity among all ages and observed an association between the two after a correction for several confounders or reported a higher prevalence of obesity among hookah smokers. This was confirmed by the meta-analysis. Therefore, hookah smoking seems to be associated with a higher risk of obesity. Public health policymakers should be aware of this for the better management of obesity and weight-related comorbidities. Full article
(This article belongs to the Special Issue Nutrition, Genetics, and Cardiovascular Disease)
Figures

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Open AccessFeature PaperReview
An Update on the Tissue Renin Angiotensin System and Its Role in Physiology and Pathology
J. Cardiovasc. Dev. Dis. 2019, 6(2), 14; https://doi.org/10.3390/jcdd6020014
Received: 10 February 2019 / Revised: 18 March 2019 / Accepted: 26 March 2019 / Published: 29 March 2019
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Abstract
In its classical view, the renin angiotensin system (RAS) was defined as an endocrine system involved in blood pressure regulation and body electrolyte balance. However, the emerging concept of tissue RAS, along with the discovery of new RAS components, increased the physiological and [...] Read more.
In its classical view, the renin angiotensin system (RAS) was defined as an endocrine system involved in blood pressure regulation and body electrolyte balance. However, the emerging concept of tissue RAS, along with the discovery of new RAS components, increased the physiological and clinical relevance of the system. Indeed, RAS has been shown to be expressed in various tissues where alterations in its expression were shown to be involved in multiple diseases including atherosclerosis, cardiac hypertrophy, type 2 diabetes (T2D) and renal fibrosis. In this chapter, we describe the new components of RAS, their tissue-specific expression, and their alterations under pathological conditions, which will help achieve more tissue- and condition-specific treatments. Full article
(This article belongs to the Special Issue Nutrition, Genetics, and Cardiovascular Disease)
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