Special Issue "The Relationship between Nutrition and Diseases 2.0"

A special issue of Diseases (ISSN 2079-9721).

Deadline for manuscript submissions: 15 April 2023 | Viewed by 2884

Special Issue Editor

Prof. Dr. Marwan El Ghoch
E-Mail Website
Guest Editor
Department of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, P.O. Box 11-5020 Riad El Solh, Beirut 11072809, Lebanon
Interests: clinical nutrition; obesity; sarcopenic obesity; type 2 diabetes; eating disorders; weight-related diseases; body composition; weight cycling; physical activity; energy expenditure
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Special Issue Information

Dear Colleagues,

Diseases is launching a Special Issue entitled “The Relationship between Nutrition and Diseases”. Diseases is an international, peer-reviewed, open-access, multidisciplinary journal that focuses on the latest and most outstanding research on diseases and conditions. It is published quarterly online by MDPI. The first Issue was released in 2013.

Hippocrates said “Let food be thy medicine, and let medicine be thy food”, and since then there has been a great and growing interest in studying the potential link between nutrition and disease, mainly under two disciplines: “nutritional epidemiology” and “lifestyle medicine”. To date, a wide spectrum of results have confirmed this link; however, many of these need to be interpreted with caution before jumping to conclusions in proposing certain nutrients as preventative and therapeutic strategies for diseases. This is because many of these findings derive from cross-sectional studies that indicate only simple associations between a certain nutrient and a specific disease, and do not provide solid information regarding any causal relationships between the two conditions.

This Special Issue will provide a platform for the presentation of recent advances in knowledge of the “real” relationships between nutrition and disease, coming from diverse scientific disciplines.

Prof. Dr. Marwan El Ghoch
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diseases is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiovascular diseases
  • diabetes
  • obesity
  • cancer dyslipidemia
  • clinical nutrition
  • weight-related morbidities
  • sarcopenia
  • eating disorders
  • gut microbiota
  • anorexia and bulimia nervosa
  • binge-eating disorder
  • depression

Published Papers (3 papers)

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Research

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Article
Functional Gastrointestinal Diseases and Dietary Practices among Pakistani Children—A Schools Based Cross-Sectional Study
Diseases 2022, 10(4), 103; https://doi.org/10.3390/diseases10040103 - 16 Nov 2022
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Abstract
Background: Functional gastrointestinal diseases (FGIDs) are an important yet highly under explored area among public health issues. FGIDs’ complex etiology makes them of interest along with their prevalence in children steadily increasing, especially in the developing world. We aimed to determine the burden [...] Read more.
Background: Functional gastrointestinal diseases (FGIDs) are an important yet highly under explored area among public health issues. FGIDs’ complex etiology makes them of interest along with their prevalence in children steadily increasing, especially in the developing world. We aimed to determine the burden FGIDs pose on school-going children, and to determine its association with the dietary intake patterns in Pakistani children. Methodology: The study included 385 school-children from public and private schools in Pakistan through multistage random sampling, from March to August 2022. We used the Food Frequency Questionnaire (FFQ) and Rome IV Criteria for a comprehensive exploration of the issue. Associations between the FGIDs and dietary factors were analyzed using chi-square and Fischer’s exact tests in SPSS version 26.0. Results: Females constituted 77.4% (n = 298) of all respondents, while 44.9% (n = 173) of the total reported a family history of gastrointestinal diseases. FFQ analysis showed varying consumption frequencies for different food groups. Functional abdominal pain and irritable bowel syndrome (IBS) were the highest reported FGIDs with a prevalence of 38.7% (n = 149) and 24.9% (n = 96), respectively. Statistical associations were found between different FGIDs and gender, age, household income, family members, and dietary variables such as fruit, vegetable, beverage and pulse consumption. Conclusion: FGIDs were found to be associated with a number of socio-demographic and dietary factors which calls for small scale and large scale attention to the issue. Results from the current study and further studies may help develop guidelines to manage these disorders in Pakistan. Full article
(This article belongs to the Special Issue The Relationship between Nutrition and Diseases 2.0)
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Opinion
Tricking the Brain with Leptin to Limit Post Liposuction and Post Bariatric Surgery Weight Regain?
Diseases 2022, 10(4), 80; https://doi.org/10.3390/diseases10040080 - 04 Oct 2022
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Abstract
Obesity represents a medical challenge for modern therapists. The main difficulty is that once obesity is established, it is hard to reverse. It is believed that once an increased body weight/adiposity content is reached it becomes the “reference” that energy mechanisms adjust towards [...] Read more.
Obesity represents a medical challenge for modern therapists. The main difficulty is that once obesity is established, it is hard to reverse. It is believed that once an increased body weight/adiposity content is reached it becomes the “reference” that energy mechanisms adjust towards keeping. Thus, following a weight loss, such as following liposuction/bariatric surgery, the metabolic balance would target this “reference” that represents the previously reached body weight/adiposity content. On the other hand, medical procedures of liposuction and bariatric surgery reduce the level of the adipocytes-produced hormone leptin. This leptin level reduction leads to an increase in food intake and a decrease in energy expenditure. Therefore, the reduced leptin would be among the signals received by the brain to trigger weight regain via processes aiming to re-establish the pre-liposuction/pre-bariatric surgery body weight or adiposity content. We suggest administering leptin so that the brain does not detect the post- liposuction/post-bariatric surgery weight loss; thus, limiting the signals toward weight regain, leading to a better weight control. Full article
(This article belongs to the Special Issue The Relationship between Nutrition and Diseases 2.0)
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Opinion
In Vitro Mimicking of Obesity-Induced Biochemical Environment to Study Obesity Impacts on Cells and Tissues
Diseases 2022, 10(4), 76; https://doi.org/10.3390/diseases10040076 - 03 Oct 2022
Cited by 1 | Viewed by 968
Abstract
Obesity represents a heavy burden for modern healthcare. The main challenge facing obesity research progress is the unknown underlying pathways, which limits our understanding of the pathogenesis and developing therapies. Obesity induces specific biochemical environments that impact the different cells and tissues. In [...] Read more.
Obesity represents a heavy burden for modern healthcare. The main challenge facing obesity research progress is the unknown underlying pathways, which limits our understanding of the pathogenesis and developing therapies. Obesity induces specific biochemical environments that impact the different cells and tissues. In this piece of writing, we suggest mimicking obesity-induced in vivo biochemical environments including pH, lipids, hormones, cytokines, and glucose within an in vitro environment. The concept is to reproduce such biochemical environments and use them to treat the tissue cultures, explant cultures, and cell cultures of different biological organs. This will allow us to clarify how the obesity-induced biochemistry impacts such biological entities. It would also be important to try different environments, in terms of the compositions and concentrations of the constitutive elements, in order to establish links between the effects (impaired regeneration, cellular inflammation, etc.) and the factors constituting the environment (hormones, cytokines, etc.) as well as to reveal dose-dependent effects. We believe that such approaches will allow us to elucidate obesity mechanisms, optimize animal models, and develop therapies as well as novel tissue engineering applications. Full article
(This article belongs to the Special Issue The Relationship between Nutrition and Diseases 2.0)
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