Novel Insights Into Heart Failure With Preserved Ejection Fraction (HFpEF): From Pathophysiology to Precision Management
A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Acquired Cardiovascular Disease".
Deadline for manuscript submissions: 31 January 2027
Editors
Interests: coronary artery disease; heart failure; cardiac imaging
Interests: heart failure; endothelial progenitor cells; endothelium; myocardial infarction; revascularization; exercise training; rehabilitation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Heart Failure with Preserved Ejection Fraction (HFpEF) represents one of the most challenging and increasingly prevalent syndromes in contemporary cardiovascular medicine. Despite preserved left ventricular ejection fraction, patients experience significant morbidity, recurrent hospitalizations, impaired quality of life, and high mortality. The heterogeneity of HFpEF reflects the complex interplay between myocardial dysfunction, vascular abnormalities, systemic inflammation, metabolic disturbances, renal impairment, aging, obesity, and other comorbidities, making accurate diagnosis, risk stratification, and therapeutic decision-making particularly demanding.
This Special Issue, “Novel Insights into Heart Failure with Preserved Ejection Fraction: From Pathophysiology to Precision Management”, aims to highlight recent advances in the understanding, diagnosis, and management of HFpEF. We welcome original research, reviews, and translational studies focusing on disease mechanisms, phenotyping, biomarkers, imaging, exercise physiology, comorbidity-driven pathways, emerging pharmacological and non-pharmacological therapies, and personalized treatment strategies. Through this collection, we seek to promote a deeper understanding of HFpEF and support the development of more precise, patient-centered approaches to improve clinical outcomes.
Prof. Dr. Ioannis Paraskevaidis
Dr. Christos Kourek
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Heart failure with preserved ejection fraction (HFpEF)
- diastolic dysfunction
- myocardial remodeling
- vascular dysfunction
- systemic inflammation
- cardiometabolic disease
- phenotyping
- biomarkers
- cardiovascular imaging
- risk stratification
- precision medicine
- SGLT2 inhibitors
- exercise intolerance
- comorbidities
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