Drosophila suzukii: Interactions of Microorganisms or Metazoans with the Immune System

A special issue of Insects (ISSN 2075-4450). This special issue belongs to the section "Insect Behavior and Pathology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 324

Special Issue Editors


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Guest Editor
Laboratory of Comparative Immunology and Parasitology, University of Insubria, 21100 Varese, Italy
Interests: insect immunity; innate immunity; parasitology; nematodes; host–parasite interaction
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Laboratory of Comparative Immunology and Parasitology, Department of Theoretical and Applied Sciences, University of Insubria, 21100 Varese, Italy
Interests: Drosophila suzukii; steinernema carpocapsae; xenorhabdus nematophila; humoral defenses; cellular defenses; entomopathogenic nematodes; entomopathogen surface; nematodes; bacillus thuringiensis; fungi; wasps; insect immunity; insects

Special Issue Information

Dear Colleagues,

Drosophila suzukii, an invasive fruit fly, is a major agricultural pest; it causes significant damage to soft-skinned fruits. Chemical control has limited effectiveness, given the rapid life cycle and the protected environment in which the larvae develop. Biological control strategies include the introduction of natural enemies, such as parasitoid wasps, predatory insects, nematodes, and entomopathogenic fungi. It is well known that bioinsecticides base their efficacy on the ability to evade and/or neutralize host immune defense processes. Therefore, the study of the physiological relationships between host and bioinsecticide is fundamental to the development of effective and innovative methods for the control of insect pests. The goal of this Special Issue is to gather up-to-date information on the efficacy of bioinsecticides in relation to the immune response of D. suzukii.

Dr. Maurizio Francesco Brivio
Dr. Maristella Mastore
Guest Editors

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Keywords

  • Drosophila suzukii
  • immune system
  • parasitoids
  • entomopathogen nematodes
  • entomopathogen microorganisms
  • entomopathogen secondary metabolites

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Published Papers (1 paper)

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Research

19 pages, 3718 KB  
Article
Evaluation of the Insecticidal Potential of Lysinibacillus fusiformis Against Drosophila suzukii Larvae
by Maristella Mastore, Elisa Broggio, Davide Banfi, Ricardo A. R. Machado, Aashaq Hussain Bhat, Sadreddine Kallel, Marcella Reguzzoni, Silvia Quadroni and Maurizio F. Brivio
Insects 2025, 16(11), 1090; https://doi.org/10.3390/insects16111090 (registering DOI) - 24 Oct 2025
Abstract
The increase in the world population and consequent rise in food demand have led to the extensive use of chemical pesticides, causing environmental and health concerns. In response, biological control methods, particularly those involving microbial agents, have emerged as sustainable alternatives within integrated [...] Read more.
The increase in the world population and consequent rise in food demand have led to the extensive use of chemical pesticides, causing environmental and health concerns. In response, biological control methods, particularly those involving microbial agents, have emerged as sustainable alternatives within integrated pest management. This study highlights the potential of Lysinibacillus fusiformis as a biocontrol agent against the dipteran Drosophila suzukii (Matsumura) (Diptera: Drosophilidae), a pest responsible for damaging soft-skinned fruits. Experimental treatments using vegetative cells, spores, and secondary metabolites of L. fusiformis on D. suzukii larvae demonstrated significant larvicidal effects, accompanied by observable changes in gut morphology under microscopy. Moreover, preliminary immunological assays showed the interference of this bacterium with the host immune system. All the results indicate the suitability of L. fusiformis for its possible integration into sustainable agricultural practices, although additional research is required to understand its applicability in the field. Full article
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