Preimplantation Genetic Testing in Assisted Reproductive Technologies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 1156
Special Issue Editor
Interests: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology
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Special Issue Information
Dear Colleagues,
Assisted reproductive technology (ART) has undergone remarkable progress since the birth of the first IVF baby in 1978, revolutionizing the field of reproductive medicine. The technological advancements in ART, particularly in micromanipulation techniques and the improvement of culture conditions, have enabled more precise fertilization, trophectoderm biopsy and embryo development. These innovations have not only addressed male infertility issues but have also significantly reduced the incidence of multiple pregnancies, a common concern with early ART methods. As a result, ART has contributed to improved pregnancy outcomes and healthier pregnancies overall.
In the United States alone, approximately 2% of all newborns are conceived through ART, highlighting the growing role of these technologies in modern reproductive healthcare. A key development in ART has been the introduction of preimplantation genetic testing (PGT), which has become a critical tool in the embryo selection process. PGT allows clinicians to screen embryos for genetic abnormalities before implantation, ensuring the selection of embryos that are either genetically normal or carry a lower risk of inheriting specific genetic disorders. This has greatly enhanced the likelihood of a successful pregnancy and live birth, while also helping to prevent the transmission of inheritable genetic conditions.
This Special Issue focuses on the various aspects of molecular screening during the preimplantation stage, aiming to enhance live birth rates and reduce the risk of unexpected miscarriages.
Dr. Sung Tae Kim
Guest Editor
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Keywords
- preimplantation genetic testing
- embryo selection
- in vitro fertilization
- infertility
- implantation failure
- miscarriage
- mosaicism
- segmental aneuploidy
- non-invasive technology
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