Special Issue "Tuberculosis and Non-tuberculous Mycobacteria (NTM) Infections"

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Infectious Disease Epidemiology".

Deadline for manuscript submissions: 31 May 2021.

Special Issue Editor

Prof. Dr. Giovanni Sotgiu
Guest Editor
Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy
Interests: tuberculosis; NTM; respiratory infections; epidemiology; medical statistics

Special Issue Information

Dear Colleagues,

Mycobacterial infections can represent an important clinical and public health threat worldwide. Tuberculosis (TB), together with malaria and HIV/AIDS, is one of the most important infectious diseases in terms of incidence and mortality. The heterogeneous geographical distribution of TB cases is characterized by a high incidence in low- and middle-income countries. However, several TB outbreaks have been described in hospitals, schools, or congregate settings located in high-income countries. The emergence and spread of TB/HIV co-infection and multidrug-resistant TB (MDR-TB) have contributed to complicate the clinical and public health management of the disease.

Furthermore, several authors have described an increased incidence and prevalence of non-tuberculous mycobacteria (NTM) disease. Pulmonary and extra-pulmonary forms have been diagnosed in immunocompromised patients and in individuals with chronic medical conditions (e.g., bronchiectasis, cystic fibrosis, chronic obstructive pulmonary disease). New efforts in the research field are needed to clarify the pathogenesis of NTM infections, to assess the accuracy of new diagnostic approaches and the efficacy of novel therapeutic interventions.

Prof. Dr. Giovanni Sotgiu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Tuberculosis (TB)
  • NTM

Published Papers (1 paper)

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Open AccessArticle
Prevalence and Risk Factors of Latent Tuberculosis Infection (LTBI) in Patients with Type 2 Diabetes Mellitus (T2DM)
Int. J. Environ. Res. Public Health 2021, 18(1), 305; https://doi.org/10.3390/ijerph18010305 - 04 Jan 2021
Type 2 diabetes mellitus (T2DM) and tuberculosis (TB) together impose a high disease burden in terms of both mortality and health economics worldwide. The objective of this study was to estimate the prevalence and risk factors of latent TB infection (LTBI) in patients [...] Read more.
Type 2 diabetes mellitus (T2DM) and tuberculosis (TB) together impose a high disease burden in terms of both mortality and health economics worldwide. The objective of this study was to estimate the prevalence and risk factors of latent TB infection (LTBI) in patients with T2DM in Malaysia. A cross-sectional study was performed, and adult T2DM patients (n = 299) were included. Simple and multiple logistic regression analyses were performed to identify the LTBI-associated risk factors in patients with T2DM. Multiple logistic regression was used to estimate adjusted odds ratios (aOR) and 95% confidence intervals (CIs) between T2DM and LTBI and was adjusted for potential confounders. The prevalence of LTBI in patients with T2DM was 11.4% (95% CI: 8.0–15.0%). There was no significant difference in the socio-demographic characteristics between LTBI and non-LTBI subjects. No significant difference in the smoking status, the duration of smoking, and the duration of T2DM, HbA1c, or treatments was observed. Interestingly, a higher level of education was observed to be associated with a lower prevalence of LTBI in T2DM patients (aOR: 0.08, 95% CI: 0.01–0.70, p = 0.02). Although the prevalence of LTBI in T2DM was low, it is important to screen for it in T2DM patients due to the risk of developing severe active TB. Full article
(This article belongs to the Special Issue Tuberculosis and Non-tuberculous Mycobacteria (NTM) Infections)
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