Dear Colleagues,

In contrast to what is known about the various acute and chronic responses to hypoxia (i.e., the lowering of the inspiratory oxygen partial pressure), far less is known about the acute and especially the chronic responses to exposure to hyperoxia (i.e., elevation of the fractional oxygen content (F_inO₂) of the air). In hyperoxia, the oxygen content of the arterial blood augments primarily due to physically dissolved oxygen, since arterial hemoglobin is nearly fully saturated in normoxia. With elevated F_inO₂, the arterial pO₂ increases and the pO₂-gradient between blood and tissue reduces the limitations in peripheral diffusion, thereby explaining improved oxygen utilization in hyperoxia. This chain of mechanisms may be especially important during exercise because during heavy exercise the arterial oxygen saturation may decline notably, and thus hyperoxia is a measure to diminish exercise-induced hypoxemia.

I am pleased to announce this Special Issue in the International Journal of Environmental Research and Public Health (IJERPH) entitled “Effects of Hyperoxic Training on Acute Responses and Exercise Performance”. This collection of important high-quality papers focuses on the current state of knowledge and cutting-edge developments in hyperoxic exercise and the practical applications for training. We consider that this Issue will be the best forum for disseminating excellent research findings as well as sharing innovative ideas in the field. Manuscripts dealing with new aspects and approaches to training and exercising under hyperoxic conditions investigating the acute physiological and psychological responses as well as chronic effects and adaptations are welcome. Original research papers, reviews, case reports, and other types of manuscripts are welcome.

You are welcome to send a tentative title and a short abstract to our Editorial Office ([email protected]) for evaluation before submission. Please note that selected full papers will still be subjected to a thorough peer-review.

I look forward to receiving your excellent work.

Prof. Dr. Christoph Zinner
Guest Editor

Manuscript Submission Information

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• acclimation
• hyperoxia
• maximal oxygen uptake
• oxygen partial pressure
• endurance training
• oxygen transport