Special Issue "Emergence and Re-Emergence of Mumps Virus Infection"

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Infectious Disease Epidemiology".

Deadline for manuscript submissions: closed (31 October 2019).

Special Issue Editor

Prof. Kow-Tong Chen
E-Mail Website
Guest Editor
Department of Public Health, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan
Tel. 886-933890260
Interests: infectious disease epidemiology; field epidemiology; outbreak investigation; environmental factors
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Mumps is highly infectious and spreads rapidly in susceptible individuals living in close proximity. In the pre-vaccination era, the highest attack rate was among primary school children and most adolescents. Although immunization of two doses of the measles–mumps–rubella (MMR) vaccine is part of a worldwide childhood vaccination program, cases of mumps continue to occur annually, including outbreaks with thousands of cases reported. The reasons for this trend are still unclear. There is a need for further scientific evidence to work on preventing the emergence of mumps virus (MuV) infection.

This Special Issue provides an opportunity to publish papers on environmental research in MuV infection, as well as public issues with respect to MuV infection. The focus of this Special Issue is on the mechanism of emerging MuV infection; we emphasize interdependence between humans and non-human species in complex socio-ecological systems, and the environmental factors affecting MuV transmission. Authors are invited to submit original articles, systemic reviews and meta-analysis, and critical reviews and short communications addressing all the relevant issues to highlight any recent advance in MuV infections and transmission, and their impact on individual and public health.

The submission deadline is 31 October 2019. You may send your manuscript now or up until the deadline. Submitted papers should not be under consideration for publication elsewhere. We also encourage authors to send a short abstract or tentative title to the Editorial Office for announcement on this website.

Prof. Kow-Tong Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • emergence
  • mumps
  • vaccine
  • immunity
  • epidemiology
  • cell-immunity
  • seroconversion

Published Papers (1 paper)

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Open AccessArticle
Epidemiological Characteristics and Spatiotemporal Analysis of Mumps from 2004 to 2018 in Chongqing, China
Int. J. Environ. Res. Public Health 2019, 16(17), 3052; https://doi.org/10.3390/ijerph16173052 - 22 Aug 2019
Mumps vaccines have been widely used in recent years, but frequent mumps outbreaks and re-emergence around the world have not stopped. Mumps still remains a serious public health problem with a high incidence in China. The status of mumps epidemics in Chongqing, the [...] Read more.
Mumps vaccines have been widely used in recent years, but frequent mumps outbreaks and re-emergence around the world have not stopped. Mumps still remains a serious public health problem with a high incidence in China. The status of mumps epidemics in Chongqing, the largest city in China, is still unclear. This study aimed to investigate the epidemiological and spatiotemporal characteristics of mumps and to provide a scientific basis for formulating effective strategies for its prevention and control. Surveillance data of mumps in Chongqing from January 2004 to December 2018 were collected from the National Notifiable Diseases Reporting Information System. A descriptive analysis was conducted to understand the epidemiological characteristics. Hot spots and spatiotemporal patterns were identified by performing a spatial autocorrelation analysis, a purely spatial scan, and a spatiotemporal scan at the county level based on geographic information systems. A total of 895,429 mumps cases were reported in Chongqing, with an annual average incidence of 36.34 per 100,000. The yearly incidence of mumps decreased markedly from 2004 to 2007, increased sharply from 2007 to 2011, and then tapered with a two-year cyclical peak after 2011. The onset of mumps showed an obvious bimodal seasonal distribution, with a higher peak of mumps observed from April to July of each year. Children aged 5–9 years old, males, and students were the prime high-risk groups. The spatial distribution of mumps did not exhibit significant global autocorrelation in most years, but local indicators of spatial autocorrelation and scan statistics detected high-incidence clusters which were mainly located in the midwestern, western, northeastern, and southwestern parts of Chongqing. The aggregation time frame detected by the purely temporal scan was between March 2009 and July 2013. The incidence of mumps in Chongqing from 2004 to 2018 featured significant spatial heterogeneity and spatiotemporal clustering. The findings of this study might assist public health agencies to develop real-time space monitoring, especially in the clustering regions and at peak periods; to improve immunization strategies for long-term prevention; and to deploy health resources reasonably. Full article
(This article belongs to the Special Issue Emergence and Re-Emergence of Mumps Virus Infection)
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