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Special Issue "Relationship between Drug Management and Women's Health"
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Women's Health".
Deadline for manuscript submissions: 10 January 2020.
Interests: Dopaminergic System; Brain and Behavior; Electrophysiology; Epilepsy; Hippocampus; Long-Term Potentiation; Memory Consolidation; Pharmacogenetics of Efavirenz; Sleep and Alzheimer’s Disease; Sleep and Pregnancy
There are major differences in disease prevalence, as well as variations in drug efficacy and adverse effect profiles, between men and women. Pharmacological responses clearly depend on multiple factors, including reproductive status (e.g., male vs female; prepubertal/pubertal/post-reproductive). Currently much less is known about women’s responses to medicines. Consequently, a concerted research effort is needed to address this dearth of knowledge. The cyclic nature of fluctuations in hormonal and neuronal function, and the unique events of female reproductive life (i.e., menstruation, pregnancy, lactation, and menopause) have contributed to the virtual exclusion of women from clinical trials, and of female animals from preclinical studies. Research funding bodies are now calling for the systemic integration of biological sex analyses. Sex-based differences in pharmacokinetics, pharmacodynamics and pharmacogenetics are being continuously discovered. For example, sex-related differences have been reported for gastric acidity, intestinal motility, and liver enzymes (primarily cytochrome P450s), and renal excretion, all of which may alter plasma drug levels. Further, findings consistently demonstrate that women exhibit frequent and more severe adverse effects than do men. Some of these differences are likely hormone-related. It is time, in fact overdue, to consolidate these diverse findings. This Special Issue calls for manuscripts addressing the differential effects of medicines in women—in relation to health, disease prevention, diagnosis, evaluation and treatment. We welcome original research papers using different study designs, as well as systematic reviews and meta-analyses.
Prof. Sanika S. Chirwa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Drug Adverse Effects
- Reproductive Life
- Sex-Based Differences
- Women’s Health