Co-morbidities, Co-medications and Cancer

Dear Colleagues,

Cancer is common and rising as the population ages. It is becoming a chronic disease as cancer survival rates are improving with advances in diagnosis and treatment options. As a result, cancer patients are increasingly burdened with comorbidities such as cardiovascular disease and diabetes, which may increase their risk of being exposed to polypharmacy, i.e., the simultaneous use of multiple drugs.

Comorbidities and associated medication use may have an impact on cancer treatments and outcomes. For example, patients with comorbidities may be less likely to receive definitive cancer treatment and experience poorer survival outcomes. Polypharmacy may increase the risk of drug–drug interactions which may result in increased drug-related toxicity or impaired treatment efficacy, thereby impacting survival outcomes. On the other hand, certain noncancer medications such as metformin appear to have a positive effect on cancer outcomes.

This Topical Collection is open to the subject area of comorbidities, co-medications, and cancer. The keywords listed below provide an outline of some of the possible areas of interest.

Dr. Sandar Tin Tin
Guest Editor

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