Optimizing Exercise Interventions for Cardiovascular Health: From Prescription to Personalization

Dear Colleagues,

Cardiovascular disease remains the leading cause of morbidity and mortality worldwide, despite substantial advances in pharmacological and interventional therapies. Physical training is widely recognized as a cornerstone strategy for both the prevention and management of cardiovascular disease, exerting beneficial effects on cardiovascular structure and function, metabolic health, inflammation, and overall mortality risk. However, important gaps remain regarding the optimal type, intensity, timing, and individualization of exercise interventions across different cardiovascular conditions and populations.

The aim of this Special Issue, therefore, is to highlight original research and high-quality reviews that advance understanding of the role of exercise in the prevention and intervention of cardiovascular disease. Contributions may explore mechanistic pathways (e.g., endothelial function, autonomic modulation, inflammation, oxidative stress), clinical and population-based outcomes, and translational approaches linking experimental findings to real-world practice. Studies addressing diverse populations, comorbidities, and environmental or behavioral contexts are particularly encouraged. By integrating basic, clinical, and public health perspectives, we seek to provide evidence-based insights that support exercise as a key therapeutic strategy in cardiovascular health.

Prof. Dr. Paulo De Tarso Veras Farinatti
Dr. Juliana Pereira Borges
Guest Editors

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