Innovative Technologies in Pain Management

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: 30 December 2025 | Viewed by 1104

Special Issue Editors


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Guest Editor
1. Toledo Physiotherapy Research Group (GIFTO), Faculty of Physical Therapy and Nursing, Universidad de Castilla-La Mancha, Toledo, Spain
2. Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), Castilla-La Mancha, Spain
Interests: pain management; chronic pain; rehabilitation; physiotherapy; virtual reality
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Guest Editor
Department of Nursing and Physiotherapy, University of Cadiz, 11009 Cadiz, Spain
Interests: scientometrics; bibliometrics; science mapping analysis; mHealth; telerehabilitation; physiotherapy; physical therapy; altmetrics; chronic pain
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This call for papers seeks to gather the latest evidence on innovative technologies in pain management. The primary goal is to assemble a collection of cutting-edge research that explores the impact of new technologies on managing pain and associated variables such as anxiety, depression, sleep, and quality of life. Our aim is to facilitate a swift and rigorous selection process to promptly deliver the most compelling scientific reports in this field.

Several key areas of interest include:

  • Extended reality (XR) technologies: Investigations into the application and effectiveness of virtual reality (VR), augmented reality (AR), mixed reality (MR), and other extended reality technologies in pain management.
  • Gamification for pain relief: Exploration of the use of gamified solutions to incentivize movement and improve patient engagement and outcomes.
  • Artificial Intelligence: Research on the implementation of AI in diagnosing, predicting, and personalizing pain management strategies to enhance precision and efficacy.
  • Psychosocial variables: Studies on how technological interventions impact anxiety, depression, sleep, and overall quality of life in patients experiencing pain.
  • Interdisciplinary approaches: Examination of the integration of technological solutions with traditional pain management techniques to enhance efficacy and patient satisfaction.
  • Clinical trials and case studies: Reports on clinical trials and case studies demonstrating the practical application and benefits of these innovative technologies in real-world settings.

This call for papers welcomes a variety of contributions, including the following:

  • Original articles: Groundbreaking research presenting new findings and insights in the field.
  • Reviews: Comprehensive reviews that synthesize existing knowledge and provide a holistic overview of a specific aspect of pain management through technology.
  • Research protocols: Detailed protocols for proposed research, especially those with innovative designs for utilizing new technologies in pain management.
  • Technical notes: Contributions focusing on the technical aspects of implementing and utilizing new technologies in pain management.

Authors are encouraged to submit their work to contribute to the ongoing discourse on the transformative role of technology in pain management. This call for papers emphasizes the importance of timely and impactful research to advance our understanding and clinical applications in these critical areas of medical science.

You may choose our Joint Special Issue in Life.

Prof. Dr. Hector Beltran-Alacreu
Prof. Dr. José A. Moral-Munoz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pain management
  • extended reality (XR) technologies
  • gamification for pain relief
  • psychosocial variables
  • interdisciplinary approaches

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Published Papers (1 paper)

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Research

16 pages, 806 KB  
Article
Acceptability, Usability, and Effectiveness of a Music Video Game for Pain Management: A Crossover Study
by Jara Esteban-Sopeña, Javier Bravo-Aparicio, Iria Trillo-Charlín, Alberto Roldán-Ruiz, Hector Beltran-Alacreu and Nuria García-Magro
Healthcare 2025, 13(19), 2439; https://doi.org/10.3390/healthcare13192439 - 25 Sep 2025
Viewed by 636
Abstract
Background: The increasing use of virtual reality (VR) has extended into medical applications, including pain management through immersive mechanisms. This study aimed to evaluate the effectiveness of the Clone Hero for reducing pain intensity, threshold and tolerance. Methods: A randomized crossover trial compared [...] Read more.
Background: The increasing use of virtual reality (VR) has extended into medical applications, including pain management through immersive mechanisms. This study aimed to evaluate the effectiveness of the Clone Hero for reducing pain intensity, threshold and tolerance. Methods: A randomized crossover trial compared three conditions during a cold pressor test in 25 healthy volunteers over 35 years: playing Clone Hero (interactive), watching Clone Hero (control), or no intervention (placebo). Outcome measures included usability and acceptability (qualitative questionnaire), pain intensity (VAS), pain threshold, pain tolerance, physical activity (IPAQ), and adverse effects. Results: Twenty-five participants completed the study. Overall satisfaction was high, with 92% reporting a positive experience. The Clone Hero group showed significantly lower pain intensity scores (4.9 ± 0.49) than the placebo (5.6 ± 0.48; p = 0.037) and control groups (6.1 ± 0.42; p = 0.004). Pain threshold was higher in the Clone Hero group (74.45 ± 20.7 s) compared to the placebo (62.91 ± 18.58; p < 0.001) and control (43 ± 14.77; p = 0.001). Pain tolerance was also greater (127.6 ± 9.46 s) versus the placebo (p = 0.021) and control (p = 0.001). No serious adverse effects were reported. Conclusions: Interactive pain management interventions demonstrated high levels of acceptability and user satisfaction, and may enhance pain modulation more effectively than passive or control. Full article
(This article belongs to the Special Issue Innovative Technologies in Pain Management)
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