Special Issue "Medical Disorders and Cognition in the Elderly"
A special issue of Geriatrics (ISSN 2308-3417).
Deadline for manuscript submissions: closed (30 April 2016)
Dr. Joaquim Cerejeira
Serviço de Psiquiatria, Centro Hospitalar Universitário de Coimbra, Praceta Mota Pinto, 3000-075 Coimbra, Portugal
Interests: delirium; depression; cognitive impairment; healthcare service organization
In clinical practice, there is a significant overlap between medical and cognitive disorders. Thus, elderly patients with dementia represent up to 42% of the admissions in acute medical wards, mainly with urinary or respiratory infections, and these individuals have markedly higher mortality during hospitalization. More than 50% of these patients will develop delirium, which is independently associated with a higher risk of long-term cognitive impairment, acceleration of dementia, and reduced time to permanent institutionalization and to death. Accumulating epidemiological, clinical and pre-clinical data suggest that both chronic and acute medical conditions can have a major impact in the brain of elderly subjects, eliciting cognitive dysfunction and exacerbating the progression of dementia. Additionally, a number of medications used to treat medical conditions are implicated in reversible cognitive dysfunction (e.g., anticholinergic drugs, corticosteroids, analgesics). Reversely, recent studies have unveiled that the nervous system exerts an important regulatory role over the innate immune response to illness or injury, it being likely that an ongoing neurodegenerative process can alter the physiological responses to regain homeostasis during acute illness. Full understanding of the pathophysiological mechanisms underlying this bidirectional association is crucial to reduce the risk of cognitive decline in elderly subjects with medical comorbidities and to improve the outcome of medical disorders in patients with cognitive dysfunction. This Special Issue of Geriatrics aims to publish relevant research and review articles studying the relationship between medical disorders and cognitive function.
Topics to be covered include, but are not restricted to:
- Prevalence and impact of medical comorbidities in dementia/delirum
- Special needs of patients with dementia/delirium in health care services
- The impact of dementia in self-management of chronic medical conditions
- The impact of acute medical conditions in delirium and dementia progression
- Homeostatic adaptations to medical illness in dementia/delirium
- The impact of medications in cognitive function
- The relation between dysfunction of peripheral organs and cognitive function
- Preventive and therapeutic interventions
Dr. Joaquim Cerejeira
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Geriatrics is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) is waived for well-prepared manuscripts submitted to this issue. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- cognitive function
- anticholinergic drugs
- heart failure
- renal failure
- electrolyte imbalance
- functional decline
- health care services