Special Issue "Ciliate Genetics and Epigenetics"
Deadline for manuscript submissions: closed (31 August 2019).
Interests: RNA interference (RNAi); chromatin; siRNA and miRNA biogenesis; genetics
Interests: System biology, transcriptional and transcriptional regulation; probabilistic graphical models
Interests: molecular genetics; genomics; development; molecular microbiology
Ciliates have been well-established as model organisms to investigate genetics and epigenetics. These single cell eukaryotes have two types of nuclei: germline micro- and somatic macronuclei. Some of the first epigenetic phenomena were described in these organisms, and research over the last few decades has elucidated mechanisms that underlie these phenomena. Ciliates helped pioneer the current understanding of RNA interference, both for siRNA-mediated silencing and for small RNA-directed chromatin modification and DNA rearrangements, which provide cells a powerful tool to transmit epigenetic information to sexual progeny. Progress in our understanding of molecular mechanisms came from classical genetics studies and from genomics, post-genomics and the recent advances in epigenomics technologies.
This Special Issue provides an overview on the genetics and epigenetics in ciliates and their impacts on adaptation and evolution. We invite submissions for reviews, research articles, or short-communications reporting molecular genetics and epigenomics studies of ciliate research.
We will accept manuscripts starting in September until the deadline.
Prof. Dr. Martin Simon
Dr. Marcel Schulz
Prof. Dr. Douglas Chalker
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- RNA interference
- Non coding RNA
- Genome rearrangement
- Chromatin modification