The Regulation of mRNA Translation in Health and Disease
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".
Deadline for manuscript submissions: 15 October 2025 | Viewed by 31
Special Issue Editor
Special Issue Information
Dear Colleagues,
In this Special Issue, we will showcase recent advances in the structure, process, and regulations of mRNA translation in eukaryotic systems under homeostasis and various stresses. In addition to traditional regulatory mechanisms, such as the initiation, elongation, and termination/ribosome recycle; regulation based on AUG context, mRNA editing, the premature termination codon (PTC), the upstream open reading frame (uORF), mRNA decay, ncRNAs (especially miRNA), and other emerging mechanisms will also be addressed. Pathogenic factors and cellular processes associated with cancer development, progression, and recurrence, including cell signaling, metabolic statuses, EMT and metastasis, and immune responses in TME, will also be analyzed. Cancer therapies that target mRNA translation machinery will also be highlighted.
Dr. Jun Ling
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mRNA translation
- mRNA biology
- transcriptional regulation
- cell signaling
- cancer therapies
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
