Function and Regulatory Mechanism of MicroRNAs in Cancers

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 15 January 2026 | Viewed by 151

Special Issue Editors


E-Mail Website
Guest Editor
Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Lublin, Poland
Interests: stem cells; mesenchymal stem cells; gene expression; microRNA; cancer

E-Mail Website
Guest Editor
Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Lublin, Poland
Interests: stem cells; mesenchymal stem cells; gene expression; microRNA; breast mik; cancer
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Lublin, Poland
Interests: microRNA; cancer; gene expression; alzheimer's disease

Special Issue Information

Dear Colleagues,

MicroRNAs (miRNAs) have emerged as pivotal post-transcriptional regulators of gene expression, playing a significant role in the initiation, progression, and metastasis of various cancers. Their ability to function as oncogenes or tumor suppressors places them at the forefront of molecular oncology. This Special Issue examines the intricate regulatory networks involving microRNAs (miRNAs) in cancer biology, including their interactions with transcription factors, signaling pathways, and epigenetic mechanisms. We welcome original research articles and comprehensive reviews that investigate the functional roles of miRNAs in tumorigenesis, their potential as diagnostic and prognostic biomarkers, and their relevance as therapeutic targets. We also encourage submissions that highlight novel miRNA-based therapeutic strategies, mechanisms of resistance, and the role of miRNAs in cancer immunology. Through this Special Issue, we aim to advance our understanding of microRNA-mediated regulatory processes and translate this knowledge into clinical applications.

Dr. Alicja Petniak
Dr. Paulina Gil-Kulik
Dr. Janusz Kocki
Guest Editors

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Keywords

  • microRNAs (miRNAs)
  • cancer biomarkers
  • gene regulation
  • miRNA-based therapies
  • tumor microenvironment
  • cancer progression
  • drug resistance
  • non-coding RNAs
  • epigenetic regulation
  • cancer immunology

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Published Papers

This special issue is now open for submission.
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