Genomics of Glioblastoma: Advances in Diagnosis, Treatment Strategies, and Prognostication
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Neurogenomics".
Deadline for manuscript submissions: 5 July 2025 | Viewed by 87
Special Issue Editors
Interests: glioblastoma; genetics; molecular markers; precision medicine; immunotherapy; genomics
Special Issue Information
Dear Colleagues,
Glioblastoma multiforme (GBM) remains one of the most challenging cancers to treat due to its aggressive nature, high heterogeneity, and resistance to conventional therapies. Recent advancements in genomic technologies have revolutionized our understanding of GBM, offering insights into its molecular underpinnings and paving the way for personalized medicine approaches. This Special Issue aims to explore the latest developments in the genomics of GBM, focusing on how these insights can enhance diagnosis, prognosis, and treatment strategies.
We invite contributions that delve into genomic alterations and their clinical implications, discussing the identification of key genetic mutations, such as those in IDH1, TP53, and TERT genes, and their impact on patient outcomes. Additionally, we seek articles on molecular subtyping, exploring novel molecular markers and their influence on treatment decisions. Immunotherapy and genomic targeting are also of interest, with studies on how genomic data can inform strategies like immune checkpoint inhibitors, CAR-T cell therapy, and personalized vaccines. Epigenetics and resistance mechanisms, particularly DNA methylation patterns and their role in chemotherapy resistance, are crucial topics. We will accept original research articles, clinical papers, full and mini-reviews to provide a comprehensive overview of the field. Join us in this endeavor to advance the field and improve patient outcomes through the lens of genomics.
Dr. Ankush Chandra
Dr. Yoshua Esquenazi
Guest Editors
Manuscript Submission Information
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Keywords
- glioblastoma
- genetics
- molecular markers
- precision medicine
- immunotherapy
- genomics
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