Advances in Implantable Gel-Based Materials for Cosmetic Applications
A special issue of Gels (ISSN 2310-2861). This special issue belongs to the section "Gel Processing and Engineering".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 67
Special Issue Editors
Interests: biomaterials; physicochemical characteristics of dermal fillers; filler-induced vascular occlusion; hyaluronic acid gels
Interests: biomaterials; wound healing; membranes; coatings; electrochemistry; batteries; supercapacitors; catalysis; gel strength
Special Issue Information
Dear Colleagues,
The rapid evolution of implantable biomaterials has led to a breadth of novel therapeutic indications in the field of plastic surgery, propelling injectable dermal fillers to the forefront of non-surgical therapies. After more than two decades of evidenced biocompatibility and safety for approved cosmetic filler products—ranging from hyaluronic acid gels to CaHA-CMC and PLLA composite mixtures and dilutions—a new era of tailored application-specific product engineering has been reached. As the cosmetic indications for dermal fillers expand beyond mere tissue filling to include skeletal recontouring, dynamic rhytid effacement, and bioregenerative modalities, our new priority lies in maximizing mechanical parameters to the necessary application.
This Special Issue will attempt to bridge the gap between current problems impacting the clinical efficacy, longevity, and complication propensity of dermal fillers and individual product parameters. Specifically, this Special Issue will explore syringeable gel strength and resiliency in tissue-matched applications of bony skeletal contouring or projection and the treatment of dynamic expression lines, emphasizing novel, nascent technologies. Additionally, it will explore the impact of material parameters, such as cohesion and implant-tissue interactions, necessary for passive filling and volume-correction applications and their relevance in material biointegration and bioregenerative applications. Finally, this Special Issue will also delve into the role of material parameters in facilitating or preventing material complications, including product migration/displacement, loss of clinical efficacy, chronic edema/lymphatic dysfunction, cold and inflammatory nodules, biofilm-forming bacterial infections, and arterioembolic injuries. We hope this Special Issue will encourage the continued effort to objectively evaluate product performance and guide the tailored engineering of future products.
Dr. Danny Soares
Dr. Kausik Mukhopadhyay
Dr. Thomas Kean
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Gels is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- hyaluronic acid (HA) gels
- calcium hydroxyapatite (CaHA)
- carboxymethyl cellulose (CMC)
- poly-L-lactic acid (PLLA)
- gel strength
- resiliency
- cohesion
- viscoelasticity
- mechanical properties
- material biointegration
- product migration
- displacement
- chronic edema
- lymphatic dysfunction
- inflammatory nodules
- cold nodules
- biofilm infections
- arterioembolic injuries
- next-generation dermal fillers
- material-–tissue interactions
- advanced filler technologies
- regenerative aesthetics
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