New Horizons in the Diagnosis, Prevention and Treatment of Peripheral Artery Disease in Diabetes
A special issue of Diabetology (ISSN 2673-4540).
Deadline for manuscript submissions: 20 February 2026 | Viewed by 48
Special Issue Editor
2. Cardiovascular Internal Medicine Unit, Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168 Roma, Italy
Interests: cardiovascular medicine; atherosclerosis; heart failure; peripheral artery disease; vascular complications in diabetes; role of inflammation and biomarkers in the pathophysiology and prognosis of cardiovascular diseases; translational research aimed at identifying novel therapeutic strategies
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Special Issue Information
Dear Colleagues,
Peripheral artery disease (PAD) is a common and severe complication of diabetes, traditionally associated with lower limb ischemia and risk of major adverse limb events (MALEs). However, growing evidence highlights PAD as a marker of systemic atherosclerosis and a strong predictor of major adverse cardiovascular events (MACE), underscoring the need for a broader clinical and pathophysiological perspective. Diabetic patients with PAD often present with multivessel involvement and systemic vascular dysfunction, which contributes to their extremely high residual cardiovascular risk despite optimal standard therapy.
This Special Issue aims to explore the evolving landscape of PAD in the context of diabetes, with a focus on early diagnosis, risk stratification, and emerging therapeutic strategies. Particular attention will be given to novel circulating and imaging biomarkers that may improve patient profiling and guide personalized interventions. In addition, recent advances in pharmacological and revascularization therapies will be discussed, along with their impact on both limb and cardiovascular outcomes.
By integrating current evidence with innovative research, this collection of articles will provide a comprehensive overview of the latest insights into PAD as a systemic, diabetes-related disease and highlight future directions for improving patient care.
Dr. Federico Biscetti
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diabetology is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- peripheral artery disease (PAD)
- major adverse limb events (MALE)
- major adverse cardiovascular events (MACE)
- residual cardiovascular risk
- biomarkers
- cardiovascular complications of diabetes
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