Advances in Preparation, Characterization and Application of Hydroxyapatite-Based Materials

A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Hybrid and Composite Crystalline Materials".

Deadline for manuscript submissions: 20 April 2026

Special Issue Editors


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Guest Editor
Departamento de Ingeniería, Universidad del Valle de México, Campus Querétaro. Blvd. Juriquilla No. 1000 A, Del. Santa Rosa Jáuregui, Querétaro 76230, Mexico
Interests: nanomaterials; hydroxyapatite; biomaterials; ceramics

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Guest Editor
Graduate and Research Division, Engineering Faculty, Universidad Autónoma de Querétaro, Cerro de las Campanas, Santiago de Querétaro 76010, Querétaro, Mexico
Interests: polymers; composite materials; nanobiomaterials
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Special Issue Information

Dear Colleagues,

Hydroxyapatite (HAp) has emerged as a biomaterial of outstanding scientific and technological relevance due to its excellent biocompatibility, bioactivity, and chemical similarity to the mineral component of human bone and teeth. Recent research efforts have focused on tailoring its structural, morphological, and functional properties to address pressing challenges in regenerative medicine, drug delivery, catalysis, environmental remediation, and dental applications.

This Special Issue aims to present recent advances in the synthesis, doping, surface modification, and composite development of HAp-based materials. We welcome contributions that deepen our understanding of structure–property relationships through advanced characterization techniques, as well as studies that explore innovative applications in biomedical, dental, environmental, and industrial contexts.

Topics of interest include but are not limited to:

  • Novel synthetic routes and green chemistry approaches to hydroxyapatite;
  • Functionalization and doping with metallic and non-metallic ions;
  • Nanostructured and hierarchical HAp materials;
  • Advanced characterization (FTIR, XRD, TEM, etc.) and in vitro/in vivo evaluation;
  • Applications in bone regeneration, dental restoration and implants, antimicrobial coatings, biosensors, water treatment, and cultural heritage.

Dr. Nestor Méndez-Lozano
Dr. Rodrigo Rafael Velázquez Castillo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Crystals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2100 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydroxyapatite
  • synthesis
  • doping
  • crystallization process
  • nucleation mechanisms
  • crystal growth
  • crystal structure
  • morphology
  • biomaterials
  • dental applications

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Published Papers

This special issue is now open for submission.
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