Electrochemical Bio/Sensors for Biological and Pharmaceutical Analysis

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Electrochemical Devices and Sensors".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 149

Special Issue Editor


E-Mail Website
Guest Editor
College of Science, Engineering and Technology, University of South Africa, UNISA, P.O. Box 392, Johannesburg 0003, South Africa
Interests: electrochemistry; electrochemical sensors/biosensors; analytical chemistry; material sciences

Special Issue Information

Dear Colleagues,

Electrochemical biosensor systems are very important in monitoring biological and pharmaceutical contaminants. These biosensors are not limited to enzymatic-based sensors, aptasensors, or immunosensors in applications such as diagnostics or water quality management. Direct analysis on the electrodes modified with nanomaterials are also important for measuring oxidation or reduction analysis of the analytes, although direct analysis on the electrodes may have limitations such as sensitivity, selectivity, and limit of detection. The use of nanomaterials comes into play to overcome such limitations and improve the performance of the biosensor systems for monitoring various analytes in the environment and in our bodies.

This Special Issue will encompass original research papers and reviews to benefit readers with knowledge of the electrochemical biosensors for biological and pharmaceutical analysis.

Prof. Dr. Usisipho Feleni
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemical sensors/biosensors
  • electrocatalysis
  • pharmaceuticals

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

14 pages, 2913 KiB  
Article
Sensitive Gold Nanostar-Based Adsorption Sensor for the Determination of Dexamethasone
by Riccarda Thelma MacDonald, Keagan Pokpas, Emmanuel Iwuoha and Candice Cupido
Chemosensors 2025, 13(6), 208; https://doi.org/10.3390/chemosensors13060208 (registering DOI) - 7 Jun 2025
Abstract
Herein, a novel, highly efficient electrochemical adsorption method is introduced for detection of the potent anti-inflammatory synthetic corticosteroid, dexamethasone (DEX). Unlike conventional electrochemical techniques that rely on high reduction potentials, the proposed sensor offers an alternative adsorption-based mechanism with a gold nanostar-modified glassy [...] Read more.
Herein, a novel, highly efficient electrochemical adsorption method is introduced for detection of the potent anti-inflammatory synthetic corticosteroid, dexamethasone (DEX). Unlike conventional electrochemical techniques that rely on high reduction potentials, the proposed sensor offers an alternative adsorption-based mechanism with a gold nanostar-modified glassy carbon electrode (AuNS|GCE). This enables DEX detection at a less negative or moderate reduction potential of +200 mV, circumventing potential window limitations of a GCE and providing a suitable microenvironment for detection in biological media. DEX is known to effectively prevent or suppress symptoms of inflammation due to its small applied dosage; however, an overdose thereof in the human body could lead to adverse drug effects such as gastrointestinal perforation, seizures, and heart attacks. Therefore, a sensitive method is essential to monitor DEX concentration in biofluids such as urine. NMGA-capped AuNSs were leveraged to enhance the active surface area of the sensing platform and allow adsorption of DEX onto the gold surfaces through its highly electronegative fluorine atom. Under optimized experimental conditions, the developed AuNS|GCE sensor showed excellent analytical performance with a remarkably low limit of detection (LOD) of 1.11 nM, a good sensitivity of 0.187 µA.nM−1, and a high percentage recovery of 92.5% over the dynamic linear range of 20–120 nM (linear regression of 0.995). The favourable electrochemical performance of this sensor allowed for successful application in the sensitive determination of DEX in synthetic urine (20% v/v in PBS, pH 7). Full article
Show Figures

Figure 1

Back to TopTop