Optical Probes and Bioimaging: Recent Developments and Challenges
A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Optical Chemical Sensors".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 34
Special Issue Editors
Interests: sensors; chemosensors; biosensors; nanomaterials; biochemical and pharmaceutical analysis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The past decade has witnessed a transformative evolution in optical probes and bioimaging, propelled by groundbreaking advancements in nanomaterial engineering, including plasmonic nanomaterials and fluorescence probes, and genetically encoded sensors. These developments have significantly enhanced in vivo imaging capabilities, achieving superior resolution, sensitivity, and multiplexing performance. Concurrently, second near-infrared window (NIR-II) imaging combined with artificial intelligence (AI)-powered analytics has unlocked novel possibilities for real-time deep tissue visualization. However, challenges persist regarding biocompatibility issues, the potential long-term toxicity of probes, and scattering effects in complex biological environments. Clinical implementation faces additional obstacles in standardizing protocols and achieving cost-effectiveness. Current research emphasizes hybrid approaches that merge optical methods with synergistic technologies, augmented by machine learning for sophisticated multimodal data interpretation. Addressing these challenges will position optical bioimaging as a cornerstone of precision medicine, transforming both diagnostic frameworks and therapeutic monitoring.
Prof. Dr. Jian Wang
Prof. Dr. Chunmei Li
Guest Editors
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Keywords
- optical probes
- bioimaging
- near-infrared window (NIR-II) imaging
- machine learning
- disease diagnosis
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