Hybrid Compounds Tailoring at the Nanoscale for Biomedical Applications

Dear colleagues,

Currently, most of the common diagnostic and therapeutic agents require high doses and often do not efficiently accumulate in the target sites, resulting in side effects. Therefore, the demand for more sharp and sophisticated biomedical tools has grown. Considering the peculiar properties that appear at the nanoscale level, several nanomaterials such as polymers, ceramics, metals, etc. are employed in the biomedicine field. Today, the development of hybrid compounds arising from the combination of materials of different nature, via covalent or non-covalent bonds, represents a new frontier. The combination of functional components plays a crucial role to tune the properties of these new materials, providing also multifunctional nanosystems. Nanohybrid compounds have shown several advantages, such as tunable size, shape, and surface properties, high loading capacity, leading capacity to a specific site, and stimuli-responsive drug release kinetics. These features often lead to improving their biocompatibility and pharmacokinetic profile.

The present Special Issue aims to outline the state-of-the-art regarding the development of hybrid compounds tailoring at the nanoscale, for drug/gene delivery systems, imaging probes, tissue engineering scaffolds, vascular stents, theranostic agents, dental implants, etc. Emphasis will be given to works with a deep characterization of hybrid nanomaterials which allows explaining their peculiar properties for biomedical applications.

You may choose our Joint Special Issue in Molecules.

Dr. Giulia Neri
Dr. Enza Fazio
Dr. Carmelo Corsaro
Guest Editors

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