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Special Issue "High-Throughput Strategies for the Discovery and Engineering of Enzymes for Biocatalysis"
Deadline for manuscript submissions: 29 February 2020.
Innovations in novel enzyme discoveries impact upon a wide range of industries for which biocatalysis and biotransformations represent a great challenge, i.e., the food industry, polymers, and chemicals industry. However, the concrete use of enzymes in operating industrial processes remains almost exceptional, due to their high production cost, their poor stability, and their low reusability as long as they are not efficiently immobilized on sold carriers. Finding new enzymes that would respond to these limitations is becoming essential in a world where green chemistry will soon no longer be an option. With such an objective, key tools and technologies, such as bioinformatics (i.e., to guide mutant library design), molecular biology (to create mutants libraries), microplates/microfluidics-based methodologies along with mass spectrometry/spectroscopic/chromatographic technologies (to create high-throughput screening methods) and experimental design considerations (for optimization) become essential tools for the quick discovery, enhancement, and, moreover, industrial implementation of enzymes or whole cells in (bio)processes. These technological innovations have to be clean and sustainable integrated processes to meet the growing needs of chemical, pharmaceutical, environmental, and biorefinery industries. In this Special Issue, we mainly focus on works dealing with the high-throughput screening approach for the discovery and engineering of biocatalysts for optimizing their production in integrated processes and for their extraction/purification.
Dr. Christine HELAINE
Prof. Rénato FROIDEVAUX
Dr. Egon HEUSON
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Sources of novel enzymes
- Enzyme engineering
- Bioinformatics approach for enzyme screening
- Robotizable technologies
- High-throughput screening of enzymes
- Microfluidic devices for enzyme assays
- Mini-scale bioreactor technology
- High-throughput enzyme purification
- Molecular and biochemical characterization of enzyme
- Enzyme catalysis