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Biomedicines
Special Issues
The Omics Techniques in Obstetrical Pathologies
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The Omics Techniques in Obstetrical Pathologies

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 3915

Special Issue Editor

Dr. Silvia Visentin

E-Mail Website
Guest Editor
Gynecology and Obstetrics Unit, Department of Women’s and Children’s Health, University of Padua, Padua, Italy
Interests: intrauterine growth restriction; fetal programming; cardiovascular disease; preterm labor; congenital infection; gestazional diabetes

Special Issue Information

Dear Colleagues,

Modern omics or Multi-Omics techniques, such as Genome, transcriptome, proteome and metabolome, are currently of great attention in the scientific, medical, and obstetrics/gynecological fields.

The Omics Techniques study of the etiopathogenetic processes that underlie the development of obstetric or gynecological pathologies, such as pre-eclampsia, growth retardation, the threat of preterm birth, endometriosis, oncological pathology can lead to the identification of new therapeutic strategies. At the same time, the study of cellular, gene and transmission functions are also important. The aim of the special issue is to collect the latest research results of Omics Techniques application in obstetric diseases. 

Dr. Silvia Visentin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • genome
  • transcriptome
  • proteome
  • metabolome
  • Multi-Omics
  • obstetric pathologies
  • gynecological pathologies
  • therapy

Published Papers (1 paper)

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Review

17 pages, 1327 KiB  
Review
The Role of Omics Approaches to Characterize Molecular Mechanisms of Rare Ovarian Cancers: Recent Advances and Future Perspectives
by Yashwanth Subbannayya, Riccardo Di Fiore, Silvana Anna Maria Urru and Jean Calleja-Agius
Biomedicines 2021, 9(10), 1481; https://doi.org/10.3390/biomedicines9101481 - 15 Oct 2021
Cited by 8 | Viewed by 3232
Abstract
Rare ovarian cancers are ovarian cancers with an annual incidence of less than 6 cases per 100,000 women. They generally have a poor prognosis due to being delayed diagnosis and treatment. Exploration of molecular mechanisms in these cancers has been challenging due to [...] Read more.
Rare ovarian cancers are ovarian cancers with an annual incidence of less than 6 cases per 100,000 women. They generally have a poor prognosis due to being delayed diagnosis and treatment. Exploration of molecular mechanisms in these cancers has been challenging due to their rarity and research efforts being fragmented across the world. Omics approaches can provide detailed molecular snapshots of the underlying mechanisms of these cancers. Omics approaches, including genomics, transcriptomics, proteomics, and metabolomics, can identify potential candidate biomarkers for diagnosis, prognosis, and screening of rare gynecological cancers and can aid in identifying therapeutic targets. The integration of multiple omics techniques using approaches such as proteogenomics can provide a detailed understanding of the molecular mechanisms of carcinogenesis and cancer progression. Further, omics approaches can provide clues towards developing immunotherapies, cancer recurrence, and drug resistance in tumors; and form a platform for personalized medicine. The current review focuses on the application of omics approaches and integrative biology to gain a better understanding of rare ovarian cancers. Full article
(This article belongs to the Special Issue The Omics Techniques in Obstetrical Pathologies)
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