Advances in Pathogenesis and Treatment of Colonic Diverticular Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Drug Discovery, Development and Delivery".
Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 173
Special Issue Editor
Interests: inflammatory bowel disease (IBD); Crohn´s disease; ulcerative colitis; controlled trials in IBD; observations in rare manifestations of IBD; pharmacological studies; studies on pathogenesis of IBD
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diverticular disease of the colon (DDC) is a paradox. Its prevalence and the burden for patients and healthcare systems are steadily increasing, but scientific efforts need more support and intensified collaborative strategies. Traditionally, lifestyle factors are thought to be the pathogenetic basis for the development of diverticulosis, while recent research disputes this concept. New insights into the genetic, molecular, and pathological background of the disease have emerged lately, but a conclusive pathogenetic model is still missing. Recommendations for treatments are changing accordingly. Antibiotics as first-line therapy in diverticulitis were nearly unanimously accepted, but results from recent trials question this concept. More insight into the pathogenesis, new targets of treatment, and more interdisciplinary discussion of controversial questions is urgently needed. The focus of Biomedicines is directed towards genetic mechanisms and molecular and pathological characteristics and their translation to medicine. Thus, a Special Issue of Biomedicines is very well adapted to foster the kind of information needed.
Dr. Wolfgang Kruis
Guest Editor
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Keywords
- colonic diverticular disease
- diverticulitis
- pathogenesis
- diagnosis
- treatment
