Advanced Single-Cell Sequencing in Diseases

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular Genetics and Genetic Diseases".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 1

Special Issue Editor


E-Mail Website
Guest Editor
Pulmonary Division, Indiana University School of Medicine, Indianapolis, IN, USA
Interests: single-cell sequencing; spatial transcriptomics

Special Issue Information

Dear Colleagues,

For this Special Issue, “Advanced Single-Cell Sequencing in Diseases”, we welcome studies that apply single-cell and spatial transcriptomic analyses to explore the cellular diversity and molecular mechanisms underlying various diseases. We invite submissions that use either newly generated or publicly available single-cell datasets to perform analyses such as clustering, annotation, and visualization with UMAP, DotPlot, FeaturePlot, or comparable approaches. Studies utilizing Seurat, Scanpy, or related bioinformatics frameworks for data processing, integration, and interpretation are highly encouraged. Papers comparing disease and control conditions, identifying cell-type-specific gene expression changes, or characterizing novel cellular subpopulations across tissues and models are particularly welcome. The scope includes all disease areas and experimental systems that employ single-cell data to draw biological conclusions. Our aim is to compile a collection of data-driven analyses demonstrating how single-cell technologies and computational tools can advance our understanding of disease biology.

We look forward to receiving your contributions.

Dr. Sedat Kacar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • single-cell sequencing
  • bioinformatics analysis
  • spatial transcriptomics
  • cellular heterogeneity
  • data-driven discovery
  • disease biology

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers

This special issue is now open for submission.
Back to TopTop