Advances in Medically Assisted Reproduction
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 23
Special Issue Editor
2. Medical School, National and Kapodistrian University of Athens, Athens, Greece
Interests: infertility; assisted reproduction; reproductive endocrinology; poor ovarian response; ovarian stimulation; ovarian aging; pregnancy complications; minimally invasive surgery; hysteroscopy; endoscopy; colposcopy; evidence-based medicine
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Special Issue Information
Dear Colleagues,
Medically assisted reproduction (MAR) is one of the fastest growing areas of modern medical science. The increase in the prevalence of infertility, and by extension the ever-increasing application of MAR, renders the necessity for research imperative. The objective of the present research endeavor is threefold: firstly, to facilitate a comprehensive understanding of the pathophysiology of infertility within the paradigm of personalized and precision medicine; secondly, to optimize the extant methods of MAR; and thirdly, to identify new, safer, and more effective MAR techniques. The present research concerns all the stages that make up what is defined as MAR. This includes the following: firstly, the identification of new methods of the personalized diagnosis of infertility; secondly, the development of innovative therapeutic approaches; and thirdly, the optimization of embryo and gamete culture conditions. In order to achieve contemporary research objectives, MAR constitutes a multidisciplinary discipline where research is carried out at multiple levels, including basic, translational, and clinical research. Machine learning and artificial intelligence (AI) are currently being used in this field, as well as 'state-of-the-art' approaches such as the application of omics methods. Of particular scientific interest today is the study of epigenetics in the context of MAR, as it has become imperative to study the impact of infertility and MAR methods on the long-term health of future generations, especially considering that more than 13 million children have been born through MAR to date.
Considering the significance of improving MAR performance, we invite clinicians and reproductive scientists to contribute to this Special Issue with original research articles and narrative reviews, focusing on highlighting novel approaches to MAR. In addition, studies focusing on unveiling novel biomarkers as well as novel algorithms for accurately diagnosing and managing infertility are also invited. Finally, studies investigating novel treatments and protocols aiming to improve reproductive potential would be of added value.
We believe that a series of articles within this framework will make a valuable contribution towards better understanding and managing the multifactorial nature of MAR.
Dr. Theodoros Kalampokas
Guest Editor
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Keywords
- infertility
- medically assisted reproduction
- reproductive endocrinology
- clinical embryology
- genetics
- artificial intelligence
- epigenetics
- precision medicine
- evidence-based medicine
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