Three-Dimensional Printed Meshes in Guided Bone Regeneration
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Biomedical Engineering and Materials".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 14
Special Issue Editors
Interests: 2D/3D cell culture modelling; regenerative medicine
Interests: 2D/3D cell culture modelling; regenerative medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Guided bone regeneration (GBR), an oral surgical procedure that aims to rebuild lost bone with metallic or polymeric meshes, has become an essential component in regenerative dentistry. Recent advances in digital dental radiology, image segmentation, CAD-CAM procedures, 3D bioprinting and predictive computer simulations have made major contributions to transforming a therapy that is time-consuming, technique-sensitive, and highly dependent on the operator’s experience in an evidence-based technique assuring individualized surgery planning.
However, there are still several problems to be solved such as the frequent possibility of exposure of the mesh because of mucosal dehiscence, which can produce an infection of the surgical site. Among the causes described in the literature that can produce these drawbacks are the excessive difference in stiffness between the meshes and the overlying mucosa, the defects in gingival vascularization typical of the crestal area or caused by metabolic diseases of the patient and the type of material with which the meshes are constructed.
This Special Issue on “Three-Dimensional Printed Meshes in Guided Bone Regeneration”, therefore, will focus on original research papers and comprehensive reviews, dealing with cutting-edge experimental and computational methodologies for multiscale investigations of meshes in contact with biological tissues of the human body system. Topics of interest for this Special Issue include, but are not limited to, the following:
- Advanced experimental techniques for characterizing biological tissue contacting polymeric (Polycaprolactone) 3D printed meshes;
- Novel microstructure-based constitutive melt electrowritten meshes model;
- Growth, remodeling and repair of vascular tissue in mucosal tissues;
- Quantification of in vivo functional biomechanical properties of meshes during the bone healing;
- Investigations of the interrelationship of mucosal tissue’s biomechanical behavior with the underlying 3D printed mesh microstructure;
- Verification and validation of in vitro environment mimicking the relationships between meshes and mucosal tissue;
- Four-dimensional printing of shape-changing meshes in guided bone surgery;
- Molecular and cellular biomechanics in 3D bioprinted meshes.
All research areas are considered relevant as long as experimentations and/or predictive simulations are the main study drivers.
Dr. Giulia Guarnieri
Dr. Annamaria Morelli
Guest Editors
Dr. Claudio Cirrincione
Guest Editor Assistant
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Keywords
- 3D–4D printing
- vascular metabolism
- mucosal stiffness
- bone and gingival cells metabolism
- bioprinting
- melt electrowriting
- shape-memory materials
- titanium and polycaprolactone meshes
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