Advances in Molecular Research on Physical Activity, Sleep and Cognitive Function

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 39

Special Issue Editor

Division of Sports Science & Physical Education, Tsinghua University, Beijing 100084, China
Interests: physical activity; exercise; mental health; cognitive function; depression; sleep

Special Issue Information

Dear Colleagues,

This Special Issue, “Advances in Molecular Research on Physical Activity, Sleep and Cognitive Function”, will focus on our emerging understanding of the molecular mechanisms underlying the interplay between physical activity, sleep, and cognitive function.

Physical activity and sleep are essential lifestyle factors that significantly influence brain health and cognitive performance. While their behavioral and physiological effects have been widely studied, the molecular pathways mediating these effects remain an area of growing interest. Recent advances suggest that physical activity and sleep modulate a range of molecular processes—such as neuroinflammation, oxidative stress, synaptic plasticity, hormonal signaling, and mitochondrial function—which in turn impact cognitive outcomes across a person’s lifespan.

This Special Issue aims to highlight cutting-edge molecular research that elucidates how physical activity and sleep influence cognitive function. We welcome original research articles and comprehensive reviews that explore topics such as gene expression, proteomics, metabolomics, telomere biology, epigenetic regulation, and biomarkers related to neuroplasticity and neurodegeneration.

We cordially invite researchers from the fields of neuroscience, physiology, molecular biology, and related disciplines to contribute their findings to this rapidly evolving and interdisciplinary field.

Dr. Yanwei You
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • physical activity
  • sleep
  • cognitive function
  • molecular mechanisms
  • neuroplasticity
  • oxidative stress
  • inflammation
  • biomarkers

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Published Papers

This special issue is now open for submission.
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