The Role of DNA Repair in the Treatment of Ovarian and Breast Cancer
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 315
Special Issue Editors
Interests: cancer biology; drug repurposing; kinases; inflammatory response; neuropharmacology
Special Issue Information
Dear Colleagues,
DNA repair plays an important role in the propagation of cancer cells. DNA repair capacity also influences cancer cells’ ability to respond to treatment. While diminished DNA repair capacity can increase an individual’s risk of developing cancer, patients who harbor tumors with a high mutation burden often demonstrate improved outcomes. Paradoxically, some tumors minimize the efficacy of genotoxic chemotherapy by upregulating DNA repair machinery. In this Special Issue, we examine the effects of DNA repair on both the initiation and treatment of ovarian and breast cancers.
Dr. Justin Fortune Creeden
Dr. Daniel J. Craig
Guest Editors
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Keywords
- immunotherapy
- DNA Repair
- somatic mutations
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