Neuropeptides in Biomedicines 2.0
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2980
Special Issue Editor
Interests: neuropeptides; granin-derived peptides; eye, skin, and dental pulp; neuroprotection; glaucoma; neovascularization; endocrine orbitopathy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neuropeptides are an ever-growing family of polypeptides, which are widely distributed throughout the central and peripheral nervous systems and act as neurotransmitters and/or neuromodulators. The eye is a suitable model, since it harbors tissues related to the central nervous system, i.e., the retina, whereas the rest of the eye is innervated by the peripheral nervous system, particularly the sympathetic, parasympathetic, and sensory systems. Therefore, this sense organ serves as an ideal tool to explore peptidergic systems, and at present, the eye represents one of the best investigated organs in the body. Neuropeptides are present in the retina in amacrine and displaced amacrine cells, NPY, together with catecholamines in postganglionic sympathetic neurons, VIP; acetylcholine in postganglionic parasympathetic neurons; SP; NKA; CGRP; most granin-derived peptides; and some other peptides in sensory nerves. Their functional role has not been explored as deeply, but in the retina, it is suggested that most of them act as neuromodulators, whereas certain sensory peptides mediate the irritative response in the anterior segment of the eye—a model of neurogenic inflammation. Neuropeptides are known to be present in various other tissues of the body, and although their presence and distribution have been well explored in this case, their functional role is not fully understood, similar to the eye. In this Special Issue, manuscripts examining the presence and distribution of further neuropeptides elsewhere in the body, which have not been investigated to date, as well as studies showing novel functional findings, are welcome.
Dr. Josef Troger
Guest Editor
Manuscript Submission Information
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Keywords
- neuropeptides
- central nervous system
- peripheral nervous system
- sympathetic
- parasympathetic
- sensory
- function
