Molecular Mechanisms and Treatments on Neurodegenerative Diseases, 2nd Edition

Dear Colleagues,

Degeneration and death of neurons is the fundamental process responsible for the clinical manifestations of many different neurological disorders of aging. Age-related neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), stroke, and frontotemporal lobar dementia are highly associated with the increase in lifespan and display behavioral deficits in memory, cognition, problem solving, executive function, language, emotion, and related brain functions. At present, more than 25 million people in the world are affected by dementia, and by 2050, new cases of dementia are expected to result in nearly 1 million new cases per year. Recent studies have indicated that the most promising treatment strategy targeting the abnormal protein aggregation can reverse the pathogenesis of neurodegenerative diseases. However, the underlying mechanisms associated with neurodegeneration are not fully understood, and the efficacy of current treatments for neurodegenerative diseases are still limited. Causative factors for neurodegeneration have yet to be fully clarified. This Special Issue of Biomedicines attempts to investigate the novel mechanism involved in neurodegenerative disease models and further develop novel therapeutic strategies. Original articles and reviews are welcome for publication on the topic.

Prof. Dr. Kuen-Jer Tsai
Guest Editor

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• neurodegeneration
• neurodegenerative diseases
• dementia
• Alzheimer's disease
• Parkinson's
• disease
• frontotemporal lobar degeneration
• stroke
• brain injury
• neurogenesis
• neuroinflammation
• autophagy
• physical treatment
• drug treatment
• cell therapy

• Molecular Mechanisms and Treatments on Neurodegenerative Diseases in Biomedicines (21 articles)