Current Trends in CNS Repair and Regeneration/Neuroprotection: Mechanisms and Combating Strategies

Dear Esteemed Colleagues,

We are thrilled to announce the launch of this Special Issue, entitled "Current Trends in CNS Repair and Regeneration/Neuroprotection: Mechanisms and Combating Strategies". This Special Issue in the journal of Biomedicines delves into the pressing challenges and advancements in the field of neurodegenerative diseases. Neurodegeneration is a complex process characterized by the gradual loss of neuronal function and structure, leading to conditions such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis, among others. This collection of research articles and reviews provides an insightful overview of the latest discoveries and strategies aimed at understanding the underlying mechanisms of neurodegeneration and developing innovative approaches for neuroprotection.

Some key highlights of this Special Issue include the following:

Molecular mechanisms of neurodegeneration: Researchers explore the intricate molecular pathways involved in neurodegeneration, shedding light on factors such as protein misfolding, oxidative stress, inflammation, and mitochondrial dysfunction.

Emerging therapeutic targets: Promising therapeutic targets and drug candidates for treating neurodegenerative diseases are discussed, with a focus on potential disease-modifying approaches.

Neuroprotection strategies: The issue highlights various neuroprotective strategies, including the use of antioxidants, stem cell therapies, and gene therapies, to prevent or slow down the progression of neurodegenerative conditions.

Precision medicine and biomarkers: Advances in precision medicine and the identification of biomarkers are explored to facilitate early diagnosis and personalized treatment for patients suffering from neurodegenerative diseases.

Neuroinflammation and immune responses: Researchers delve into the role of neuroinflammation and immune responses in neurodegeneration, offering insights into potential immunomodulatory approaches.

Translational research: This Special Issue also emphasizes the importance of translational research, bridging the gap between basic science discoveries and clinical applications to bring potential neuroprotective therapies to the bedside.

This Special Issue is dedicated to advancing our understanding of cutting-edge research and innovations in the field of central nervous system (CNS) repair and regeneration. The central nervous system, comprising the brain and spinal cord, is a complex and vital component of the human body. Injuries and diseases affecting the CNS have significant implications for an individual's quality of life. Therefore, exploring the latest trends and breakthroughs in CNS repair and regeneration is of paramount importance. This Special Issue aims to provide a platform for researchers and experts to share their knowledge and insights, fostering collaboration and driving progress in this rapidly evolving field.

Topics of Interest:

We invite contributions on a wide range of topics, including but not limited to the following:

Neuroprotective efforts against different diseases, such as Alzheimer’s and Parkinson’s disease;

Neurotrophic factors, gene therapy, neuroprotection, Biomaterials, and tissue engineering for CNS repair;

Emerging technologies, such as neural implants and brain–computer interfaces;

Clinical applications and ongoing trials, ethical considerations, and regulatory aspects.

For inquiries and manuscript submissions, please contact us. We look forward to your active participation in this Special Issue. Together, let us propel the field of CNS repair and regeneration/neuroprotection to new heights.

Dr. Muhammad Sohail Khan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

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