Molecular and Cellular Research on Rare Lung Diseases

Dear Colleagues,

Rare lung diseases are associated with high mortality and morbidity and a mean survival of about 5–6 years from the onset of symptoms. They are chronic, irreversible, progressive group of disorders associated with poor prognosis. It is difficult to diagnose due to similar clinical and radiological signs. Very few treatments are now available and lung transplantation is considered the best therapeutic option in end-stage and progressive form of disease. Risk factors can include smoking, genetic predisposition and environmental variables linked to pathological alteration of lung epithelium. The exact pathogenetic mechanisms leading to the development of these disorders are not fully understood. Molecular and cellular research on this field is useful for the study of these diseases since these aspects are fundamental in the pathogenesis and progression of rare lung disease.

Dr. Laura Bergantini
Dr. Miriana d'Alessandro
Guest Editors

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