Recent Advances in Adipokines (3nd Edition)
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 898
Special Issue Editor
Interests: adipose tissue; obesity; non-alcoholic fatty liver disease; adiponectin; chemerin
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, “Recent Advances in Adipokines (3nd Edition)”, will cover a selection of original research articles and review articles related to adipokines.
Soluble proteins produced from adipose tissue are referred to as adipokines irrespective of their cellular source. White fat tissue is organized into different depots in the body. Subcutaneous and visceral adipose tissues are the best-studied compartments. Adipose tissues are also localized around organs, such as the heart and kidneys. Brown adipose tissue differs greatly from white fat and has its own set of secreted hormones, the so-called “brown adipokines”.
To date, more than 500 adipokines have been described, and most of them are associated with overweight/obesity. Whilst levels of various adipokines are increased in the serum of the obese, others decline. Associations between adipokines and cardiovascular diseases, insulin resistance, different types of cancers, and many more diseases have been identified. Further research has focused on the role of these proteins in immune responses, in autoimmune diseases, and as antimicrobial peptides. Adipokines in serum, plasma, saliva, or urine may emerge as diagnostic and/or prognostic biomarkers for various diseases.
Adipokine receptors are mostly not well characterized. Cell type and tissue expression, regulation using different metabolites, and signalling pathways have to be studied in more detail. Adipokine receptor agonists/antagonists may finally become new therapeutic targets.
Prof. Dr. Christa Büchler
Guest Editor
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Keywords
- adiponectin
- receptor
- agonist
- biomarker
- inflammation
- cancer
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