Advances in Novel Remineralizing Materials: Innovations for Sustainable Oral and Biomedical Applications
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Nanobiotechnology and Biofabrication".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 51
Special Issue Editor
Interests: dental restorative materials; bone grafts and substitutes; cell-material interactions; bioactive glasses; periodontal treatment; orthodontic adhesives
Special Issue Information
Dear Colleagues,
This Special Issue explores advances in bioactive and remineralizing materials, showcasing their transformative potential in regenerative dentistry. With escalating demands for sustainable healthcare goals, this collection emphasizes the dual pillars of ecological compatibility and clinical performance, addressing critical challenges such as dentin hypersensitivity and root caries. Covering a broad spectrum of applications—from restorative and preventive treatments to regenerative and biomedical uses—this collection welcomes interdisciplinary research on materials that exhibit improved functionality, biocompatibility, and environmental responsibility.
This Special Issue features multidisciplinary research on advanced material systems, including magnesium/zinc-doped bioactive glasses, self-assembling peptides, hydroxyapatite nanocomposites, and novel glass ionomer cements (GICs) engineered for enhanced fluoride release and mechanical durability. Studies can address various topics, including (but not limited to) remineralization, antimicrobial activity, adhesion mechanisms, mechanical reinforcement, and minimally invasive strategies.
Contributions may include in vitro studies, in vivo trials, and translational applications, elucidating mechanisms of action—from ion exchange dynamics to biomimetic apatite formation. This Special Issue particularly focuses on materials that synergize remineralization with antimicrobial properties and those that facilitate minimally invasive therapies. By curating work on material design, biocompatibility profiling, and real-world clinical validation (e.g., RCTs on dentin desensitization), this Special Issue hopes to bridge the gap between laboratory innovation and chairside practice.
Ultimately, it envisions a paradigm shift toward patient-centric, environmentally conscious solutions that redefine standards in preventive dentistry and hard-tissue engineering.
Prof. Dr. Robert Hill
Guest Editor
Florence Mai
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- dental materials
- remineralization
- bioactive glass
- glass ionomer cements
- calcium phosphate cements
- nanotechnology
- adhesion
- sustainable dentistry
- clinical performance
- biomedical engineering
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