Precision Psychiatry: A Step Toward Personalized Mental Health Care

A special issue of Behavioral Sciences (ISSN 2076-328X). This special issue belongs to the section "Psychiatric, Emotional and Behavioral Disorders".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 171

Special Issue Editors


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Guest Editor
Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy
Interests: social psychiatry; psychoeducation; public mental health; clinical psychiatry
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Guest Editor
Department of Psychiatry, Medical School, University of São Paulo, São Paulo 05403-903, SP, Brazil
Interests: social psychiatry; substance use; overdose
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Precision Psychiatry is an area of rapidly growing interest and represents a paradigmatic shift in mental health care, moving beyond traditional symptom-based classifications toward an integrative, data-driven, and individualized approach to diagnosis, prognosis, and treatment. Based on advances in neuroscience, genomics, digital phenotyping, biomarkers, and computational psychiatry, Precision Psychiatry aims to characterize the biological, psychological, and social heterogeneity that underpins mental disorders. In line with the broader movement toward personalized medicine, it also aims to tailor preventive strategies and therapeutic interventions to the unique clinical, biological, and contextual profile of each individual, overcoming the limitations of “one-size-fits-all” models.

In the current international scientific landscape, Precision Psychiatry has gained substantial strategic relevance in response to the growing global burden of mental disorders and the increasing complexity of their determinants. These include marked heterogeneity in disease phenotypes, the emergence of novel clinical presentations driven by dynamic gene–environment and epigenetic interactions, high rates of treatment resistance, and the limited predictive validity of conventional diagnostic systems, all of which call for more integrated and innovative approaches. Current evidence suggests that the integration of multi-omics data, real-world digital markers, and longitudinal clinical trajectories can enhance risk stratification, facilitate earlier detection, and support more accurate treatment selection, with potential benefits for both clinical outcomes and cost-effectiveness. Moreover, personalized mental health care is closely aligned with core ethical principles, including patient-centeredness, shared decision-making, and equity in access to innovative interventions.

This Special Issue aims to provide a critical and forward-looking platform for interdisciplinary research in Precision Psychiatry, including clinical innovation, translational neuroscience, digital mental health, and psychosocial personalization. By promoting dialog across disciplines and contexts, it seeks to contribute to the consolidation of Precision Psychiatry as a cornerstone of next-generation mental health care.

Dr. Antonio Ventriglio
Dr. João Mauricio Castaldelli-Maia
Guest Editors

Manuscript Submission Information

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Keywords

  • precision psychiatry
  • personalized mental health care
  • biomarkers in psychiatry
  • computational psychiatry
  • digital phenotyping
  • stratified psychiatry
  • translational neuroscience
  • data-driven mental health
  • treatment response prediction
  • patient-centered psychiatry

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Published Papers

This special issue is now open for submission.
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