Hearing Loss and Cognition: New Frontiers

A special issue of Audiology Research (ISSN 2039-4349).

Deadline for manuscript submissions: closed (30 April 2026) | Viewed by 1096

Special Issue Editors


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Guest Editor
ENT Unit, Department of Mental, Physical Health and Preventive Medicine, University of Campania “Luigi Vanvitelli”, 80131 Naples, Italy
Interests: sleep disorders; allergic rhinitis; endoscopic surgery; pediatric otolaryngology
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Guest Editor Assistant
ENT Unit-Department of Mental, Physical Health and Preventive Medicine, University of Campania "Luigi Van-Vitelli", 80131 Naples, Italy
Interests: nasopharyngeal and oropharyngeal cancer; head and neck oncology; otology; rhinology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Emerging evidence suggests a link between hearing loss and cognitive decline. However, the scientific evidence supporting this association remains incomplete, and further studies are needed to confirm this link. This Special Issue aims to investigate whether all hearing restoration interventions, such as hearing aids, implantable devices, and cochlear implants in adults, can prevent or at least delay cognitive decline. All study designs are welcome, and given the multidisciplinary nature of this topic, we encourage submissions that involve collaboration among otolaryngologists, audiologists, psychiatrists, neuropsychiatrists, and neurologists.

Dr. Domenico Testa
Guest Editor

Dr. Giovanni Motta
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Audiology Research is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • age-related hearing loss
  • brain plasticity
  • hearing aids
  • cochlear implants
  • implantable hearing devices
  • neurocognitive decline

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Published Papers (1 paper)

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Review

10 pages, 388 KB  
Review
Is Age-Related Hearing Loss a Modifiable Risk Factor for Cognitive Decline? Mechanisms, Evidence, and Future Directions
by Giovanni Motta, Giuseppe Tortoriello and Domenico Testa
Audiol. Res. 2026, 16(2), 61; https://doi.org/10.3390/audiolres16020061 - 21 Apr 2026
Viewed by 315
Abstract
Background: Age-related hearing loss (ARHL) is the most common sensory disorder in older adults and has been identified as a potentially modifiable risk factor for cognitive decline and dementia. Increasing evidence suggests that auditory dysfunction may contribute to adverse cognitive trajectories through [...] Read more.
Background: Age-related hearing loss (ARHL) is the most common sensory disorder in older adults and has been identified as a potentially modifiable risk factor for cognitive decline and dementia. Increasing evidence suggests that auditory dysfunction may contribute to adverse cognitive trajectories through multiple interacting pathways. This narrative review examines the mechanisms underlying the association between ARHL and cognitive decline, evaluates the impact of hearing rehabilitation, and discusses future research priorities. Methods: A narrative synthesis of epidemiological, neurobiological, and interventional studies was conducted, with emphasis on longitudinal cohort studies, neuroimaging research, and clinical investigations of hearing aids (HAs) and cochlear implants (CIs). Results: ARHL is consistently associated with accelerated cognitive decline and increased dementia risk. Proposed mechanisms include sensory deprivation-related cortical reorganization, increased cognitive load during effortful listening, shared neuropathological processes, and social disengagement. Neuroimaging studies demonstrate structural and functional alterations in auditory and associative brain regions in individuals with hearing loss. Emerging evidence suggests that HA and CI may improve cognitive performance and potentially attenuate decline, although long-term randomized data remain limited. Conclusions: Current evidence supports ARHL as a clinically relevant and potentially modifiable contributor to cognitive decline. Clarifying causal pathways and optimizing early hearing rehabilitation strategies represent key priorities for future dementia prevention research. Full article
(This article belongs to the Special Issue Hearing Loss and Cognition: New Frontiers)
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