Data Driven Modelling of Disease and Therapy Mechanisms

Dear Colleagues,

Introduction: Electrical signaling underlies communication and information exchange in all organs of all mammals, including humans. Mathematical–computational modelling of electrical activity has led to deeper insights into disease mechanisms and is increasingly being used in pre-clinical drug and device testing. A significant effort has been dedicated to developing the methods and scientific platforms (software) used in modelling. This Special Issue is designed to catalyze inter-research group interactions, thus enhancing our collective approaches.

Scope of call: This Special Issue invites contributions that use scientific platforms (software) to uncover disease mechanisms and assess treatment efficacy. We welcome contributions on the topics listed below, and other manuscripts will be considered as well.

• multi-scale cardiac electrophysiology
• multi-scale cerebral electrophysiology
• electrical modelling in other organs
• electrical activity in neuronal networks and vascular networks
• device and drug testing using modelling
• data driven simulations
• open source software and data repository announcements
• review articles
• clinical review of technology

Dr. Sanjay Kharche
Guest Editor

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