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Advanced Human–AI Interaction: Integrating Large Language Models, Large Reasoning Models and Robotic Systems

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Computing and Artificial Intelligence".

Deadline for manuscript submissions: 20 December 2025

Special Issue Editors


E-Mail Website
Guest Editor
School of Computing, Engineering and Built Environment, Glasgow Caledonian University, Glasgow G4 0BA, UK
Interests: human-computer interaction; virtual/augmented reality; artificial intelligence; simulation systems
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Institute for Advanced Modeling and Simulation, University of Nicosia, Nicosia CY-2417, Cyprus
Interests: computational fluid dynamics; turbulence; shock-waves; multi-component mixing; micro- & nano-scale flows; machine learning; artificial intelligence
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite submissions for a Special Issue on "Advanced Human–AI Interaction: Integrating Large Language Models, Large Reasoning Models and Robotic Systems".

Human–AI interaction (HAI) is rapidly evolving and becoming central to advancements across numerous fields, including smart homes, healthcare, transportation, and industrial applications. With the unprecedented rise and development of large language models (LLMs) and large reasoning models (LRMs), understanding and enhancing the interplay between humans and AI-powered robotic systems has emerged as an urgent and impactful research direction. large language models empower AI systems with sophisticated language understanding, generation, and contextual capabilities, creating more affluent, intuitive user interaction experiences. Simultaneously, emerging robotics models expand robot cognition and planning capabilities, substantially improving task execution, adaptability, and user experience. Effective integration of these advanced AI models promises smoother, safer, and more meaningful interactions between humans and robotic systems across diverse application scenarios. This Special Issue seeks original contributions and innovative research that advances the state of the art in HAI, particularly highlighting new methods, techniques, evaluation practices, and applications powered by LLMs and LRMs. Researchers are encouraged to submit theoretical analyses, rigorous experimental studies, insightful case studies, method-oriented research, and comprehensive survey and review articles in this rapidly growing field. Topics of interest include, but are not limited to, the following:

  • Human interaction frameworks and paradigms involving LLMs and LRMs;
  • Natural language interaction models with robotics and automated systems;
  • Integrating LLM and LRM for enhanced user experience and robotic intelligence;
  • Dialogue systems, multimodal interaction, and personalisation in Human–AI communication;
  • Advanced AI-driven robot assistants and robotic companions;
  • Safety, ethics and trust in interactions involving LLM- and LRM-powered robots;
  • Applications of LLMs and LRMs in smart homes, healthcare robotics, and autonomous vehicles;
  • Measuring, evaluating and benchmarking Human–AI interaction effectiveness, performance, and acceptance;
  • Simulation and virtual reality environments leveraging Human–AI interactive models;
  • Societal impact, user needs, accessibility, and inclusiveness in Human–AI interactions.

We look forward to your valuable contributions shaping future interactions between humans and AI, bridging theoretical innovation and practical deployment.

Prof. Dr. Vassilis Charissis
Prof. Dr. Dimitris Drikakis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • human–AI interaction
  • large language models
  • large reasoning models
  • robotic systems
  • practical application

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