applsci-logo

Journal Browser

Journal Browser

Artificial Intelligence (AI) in Biomedical Image Processing

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 1257

Special Issue Editors


E-Mail Website
Guest Editor
Institute of Science and Technology for Braininspired Intelligence and the MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200433, China
Interests: machine learning; medical imaging; computer vision
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Mailcode 5687, 453 Quarry Road, Palo Alto, CA 94304, USA
Interests: machine learning; medical imaging; cardiovascular medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Artificial intelligence (AI) has seen a dramatic resurgence in the past few years. With powerful computational resources and large datasets, AI is able to analyze, featuralize, predict, and generate data, endowing great potential to benefit various fields, including biomedical image processing, immensely.

On the other hand, challenges also emerge in applying AI, and the deep learning subtype in particular, to biomedical image processing. For instance, the availability of biomedical image datasets is usually limited due to the need for laborious manual labeling, privacy, and regulatory requirements. Additionally, it is hard to acquire data with different protocols, machines, and facilities, which are critical to verify the generalizability of AI algorithms. Second, the current AI algorithm is prone to small data permutations (e.g., misclassifying a panda as a gibbon with imperceptible noises). Addressing this is necessary and significant, especially in medicine and healthcare, to reduce misdiagnosis and mistreatment. Last but not least, most AI models are still considered black boxes and are hard to interpret, largely hindering their clinical usage.

This Special Issue focuses on the subject of artificial intelligence and its application in biomedical engineering, with special attention given to medical image processing. We invite authors who are interested in AI algorithms from both theoretical and practical perspectives and their applications in biomedical imaging, including, but not limited to, data acquisition, image reconstruction, image analysis and understanding, and computer-aided diagnosis.

Dr. Hongming Shan
Dr. Ruibin Feng
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • machine learning
  • image analysis
  • computer-aided diagnosis
  • visualization in biomedical imaging

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

16 pages, 17731 KiB  
Article
A Refined Approach to Segmenting and Quantifying Inter-Fracture Spaces in Facial Bone CT Imaging
by Doohee Lee, Kanghee Lee, Dae-Hyun Park, Gwiseong Moon, Inseo Park, Yeonjin Jeong, Kun-Yong Sung, Hyun-Soo Choi and Yoon Kim
Appl. Sci. 2025, 15(3), 1539; https://doi.org/10.3390/app15031539 - 3 Feb 2025
Viewed by 888
Abstract
The human facial bone is made up of many complex structures, which makes it challenging to accurately analyze fractures. To address this, we developed advanced image analysis software which segments and quantifies spaces between fractured bones in facial CT images at the pixel [...] Read more.
The human facial bone is made up of many complex structures, which makes it challenging to accurately analyze fractures. To address this, we developed advanced image analysis software which segments and quantifies spaces between fractured bones in facial CT images at the pixel level. This study used 3D CT scans from 1766 patients who had facial bone fractures at a university hospital between 2014 and 2020. Our solution included a segmentation model which focuses on identifying the gaps created by facial bone fractures. However, training this model required costly pixel-level annotations. To overcome this, we used a stepwise annotation approach. First, clinical specialists marked the bounding boxes of fracture areas. Next, trained specialists created the initial pixel-level unrefined ground truth by referencing the bounding boxes. Finally, we created a refined ground truth to correct human errors, which helped improve the segmentation accuracy. Radiomics feature analysis confirmed that the refined dataset had more consistent patterns compared with the unrefined dataset, showing improved reliability. The segmentation model showed significant improvement in the Dice similarity coefficient, increasing from 0.33 with the unrefined ground truth to 0.67 with the refined ground truth. This research introduced a new method for segmenting spaces between fractured bones, allowing for precise pixel-level identification of fracture regions. The model also helped with quantitative severity assessment and enabled the creation of 3D volume renderings, which can be used in clinical settings to develop more accurate treatment plans and improve outcomes for patients with facial bone fractures. Full article
(This article belongs to the Special Issue Artificial Intelligence (AI) in Biomedical Image Processing)
Show Figures

Figure 1

Back to TopTop