Special Issue "Novel HPLC-Assisted Method for Investigation of the Antioxidant Activity of Plant Extracts"
Deadline for manuscript submissions: 31 December 2020.
Interests: phytochemicals; phenolic compounds; ellagitannins; flavonoids; HPLC
Various phytochemicals and bioactive compounds are sourced from medicinal plants and have an impact on pharmaceutical, nutraceutical, and functional food industries. Many of these secondary plant metabolites are explored from initial identification to advanced clinical research before officially being used as pharmaceutical and nutraceutical ingredients. The development of advanced tools for the qualitative and quantitative assessment of phytochemicals, such as high-performance liquid chromatography and liquid chromatography–mass spectrometry, has enhanced the rate of bioassay-guided fractionation, significantly improving phytochemical investigation. Particular attention has been devoted to the creation of convenient and reliable methods for studying the antioxidant activity of plant extracts. A relatively new development in this field is the HPLC-assisted techniques, combining chromatographic analysis and pre-/post-column derivatization of the sample with the use of various agents, such as DPPH-HPLC or ABTS-HPLC, thereby avoiding the expensive isolation and purification steps. Given the special interest in the investigation of antioxidant activity, a promising task is the creation of correct, rapid, and inexpensive HPLC methods to determine individual compounds of plant extracts in on-line conditions. Therefore, contributions to this Special Issue may cover all research aspects related to medicinal, aromatic, and edible plant extracts; development of HPLC-assisted methods for investigation of the antioxidant activity of plant extracts; characterization of investigated plant extracts, including (but not limited to) methods for their extraction, purification, comprehensive profiling characterization, and the quantification and elucidation of their mechanisms of action with a focus on antioxidant activity.
Dr. Nina Kashchenko
Manuscript Submission Information
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- plant extracts
- antioxidant activity
- bioassay-guided techniques