Special Issue "Novel HPLC-Assisted Method for Investigation of the Antioxidant Activity of Plant Extracts"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Earth Sciences and Geography".

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editor

Dr. Nina Kashchenko
Guest Editor
Institute of General and Experimental Biology, Siberian Division, Russian Academy of Science, Ulan-Ude
Interests: phytochemicals; phenolic compounds; ellagitannins; flavonoids; HPLC

Special Issue Information

Dear Colleagues,

Various phytochemicals and bioactive compounds are sourced from medicinal plants and have an impact on pharmaceutical, nutraceutical, and functional food industries. Many of these secondary plant metabolites are explored from initial identification to advanced clinical research before officially being used as pharmaceutical and nutraceutical ingredients. The development of advanced tools for the qualitative and quantitative assessment of phytochemicals, such as high-performance liquid chromatography and liquid chromatography–mass spectrometry, has enhanced the rate of bioassay-guided fractionation, significantly improving phytochemical investigation. Particular attention has been devoted to the creation of convenient and reliable methods for studying the antioxidant activity of plant extracts. A relatively new development in this field is the HPLC-assisted techniques, combining chromatographic analysis and pre-/post-column derivatization of the sample with the use of various agents, such as DPPH-HPLC or ABTS-HPLC, thereby avoiding the expensive isolation and purification steps. Given the special interest in the investigation of antioxidant activity, a promising task is the creation of correct, rapid, and inexpensive HPLC methods to determine individual compounds of plant extracts in on-line conditions. Therefore, contributions to this Special Issue may cover all research aspects related to medicinal, aromatic, and edible plant extracts; development of HPLC-assisted methods for investigation of the antioxidant activity of plant extracts; characterization of investigated plant extracts, including (but not limited to) methods for their extraction, purification, comprehensive profiling characterization, and the quantification and elucidation of their mechanisms of action with a focus on antioxidant activity.

Dr. Nina Kashchenko
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • plant extracts
  • phytochemicals
  • HPLC
  • antioxidant activity
  • DPPH
  • ABTS
  • bioassay-guided techniques

Published Papers

This special issue is now open for submission.
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