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Advances in Precision Medicine and AI in Rheumatology and Arthritis

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 30 July 2026

Special Issue Editor


E-Mail Website
Guest Editor
First Department of Internal Medicine, Faculty of Medicine, Medical University–Varna, 9002 Varna, Bulgaria
Interests: osteoarthritis; musculoskeletal imaging and biomarkers; AI in rheumatology and rheumatic diseases

Special Issue Information

Dear Colleagues,

The field of rheumatology is undergoing a significant transformation, moving beyond traditional therapeutic approaches for inflammatory joint diseases and connective tissue diseases. This evolution is driven by unprecedented advances in therapy, particularly the development of innovative targeted biologic and targeted-synthetic drugs, which have revolutionized patient outcomes. Alongside these therapeutic breakthroughs, the field is increasingly leveraging cutting-edge technologies to usher in an era of precision medicine.

The current frontier lies in translating complex biological and clinical data into actionable insights. The implementation of artificial intelligence (AI) and machine learning is becoming pivotal for analyzing large datasets, enabling the integration of multi-omics (e.g., genomics, proteomics, metabolomics). This integration is crucial for the discovery and validation of new diagnostic and prognostic biomarkers, which are desperately needed to guide personalized treatment strategies, predict disease course, and monitor therapeutic response.

This Special Issue aims to capture the full spectrum of this progress. We invite submissions of original research, comprehensive reviews, and short communications. We are particularly interested in topics such as novel therapeutic targets, clinical trials of new drugs, AI applications in diagnostic imaging or patient stratification, multi-omics studies for biomarker discovery, and innovations in digital health for disease activity monitoring. This Special Issue aims to create a landmark collection of articles that showcase the future of rheumatology.

Dr. Tsvetoslav Georgiev
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rheumatology
  • inflammatory arthritis
  • connective tissue diseases
  • biologic DMARDs
  • targeted-synthetic DMARDs
  • artificial intelligence
  • multi-omics
  • biomarkers
  • personalized medicine

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Published Papers

This special issue is now open for submission.
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